A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs.
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mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.Herpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4HHSV-1 tegument protein and the development of its genome editing technologyShutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesmRNA stability in mammalian cellsThe herpes simplex virus type 1 vhs-UL41 gene secures viral replication by temporarily evading apoptotic cellular response to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery.The herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extractsHerpes simplex virus infection stabilizes cellular IEX-1 mRNA.Evidence that herpes simplex virus VP16 is required for viral egress downstream of the initial envelopment event.Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein.Herpes simplex virus virion host shutoff protein requires a mammalian factor for efficient in vitro endoribonuclease activity.mRNA decay during herpesvirus infections: interaction between a putative viral nuclease and a cellular translation factor.The virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNasemRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 geneHerpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?Packaging of the virion host shutoff (Vhs) protein of herpes simplex virus: two forms of the Vhs polypeptide are associated with intranuclear B and C capsids, but only one is associated with enveloped virionsAnalysis of herpes simplex virus-induced mRNA destabilizing activity using an in vitro mRNA decay system.Mutational analysis of the herpes simplex virus virion host shutoff protein: evidence that vhs functions in the absence of other viral proteinsRole of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.Herpes simplex virus VP16 rescues viral mRNA from destruction by the virion host shutoff functionIdentification and characterization of a small modular domain in the herpes simplex virus host shutoff protein sufficient for interaction with VP16.Expression and function of the equine herpesvirus 1 virion-associated host shutoff homolog.Inhibition of human immunodeficiency virus replication by the herpes simplex virus virion host shutoff protein.Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimerasThe "Bridge" in the Epstein-Barr virus alkaline exonuclease protein BGLF5 contributes to shutoff activity during productive infection.Deletion of the herpes simplex virus 1 UL49 gene results in mRNA and protein translation defects that are complemented by secondary mutations in UL41.mRNA decay during herpes simplex virus (HSV) infections: mutations that affect translation of an mRNA influence the sites at which it is cleaved by the HSV virion host shutoff (Vhs) protein.The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection.Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhsHerpes simplex virus inhibits host cell splicing, and regulatory protein ICP27 is required for this effect.Herpes simplex virus type 1 UL46 and UL47 deletion mutants lack VP11 and VP12 or VP13 and VP14, respectively, and exhibit altered viral thymidine kinase expression.Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide.In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus.Small interfering RNAs that deplete the cellular translation factor eIF4H impede mRNA degradation by the virion host shutoff protein of herpes simplex virusDifferential regulation of endogenous and transduced beta-globin genes during infection of erythroid cells with a herpes simplex virus type 1 recombinant.Control of mRNA stability by the virion host shutoff function of herpes simplex virusThe herpes simplex virus virion host shutoff function.
P2860
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P2860
A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
A mutant of herpes simplex vir ...... immediate-early (alpha) mRNAs.
@en
type
label
A mutant of herpes simplex vir ...... immediate-early (alpha) mRNAs.
@en
prefLabel
A mutant of herpes simplex vir ...... immediate-early (alpha) mRNAs.
@en
P2860
P1433
P1476
A mutant of herpes simplex vir ...... immediate-early (alpha) mRNAs.
@en
P2093
P2860
P304
P407
P577
1987-02-01T00:00:00Z