Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.
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Herpes simplex virus 1 tegument protein US11 downmodulates the RLR signaling pathway via direct interaction with RIG-I and MDA-5mRNA decay during herpes simplex virus (HSV) infections: protein-protein interactions involving the HSV virion host shutoff protein and translation factors eIF4H and eIF4A.The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genesHerpes simplex virus virion host shutoff protein is stimulated by translation initiation factors eIF4B and eIF4HShutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common ThemesReconciliation of rotavirus temperature-sensitive mutant collections and assignment of reassortment groups D, J, and K to genome segmentsInfluenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune ResponsesThe virion host shut-off (vhs) protein blocks a TLR-independent pathway of herpes simplex virus type 1 recognition in human and mouse dendritic cells.The herpes simplex virus vhs protein induces endoribonucleolytic cleavage of target RNAs in cell extractsAn important role for major histocompatibility complex class I-restricted T cells, and a limited role for gamma interferon, in protection of mice against lethal herpes simplex virus infection.Herpes simplex virus infection stabilizes cellular IEX-1 mRNA.Construction and properties of a herpes simplex virus 2 dl5-29 vaccine candidate strain encoding an HSV-1 virion host shutoff protein.Human thymidine kinase can functionally replace herpes simplex virus type 1 thymidine kinase for viral replication in mouse sensory ganglia and reactivation from latency upon explant.Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice.Optimized viral dose and transient immunosuppression enable herpes simplex virus ICP0-null mutants To establish wild-type levels of latency in vivo.Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Picornavirus internal ribosome entry site elements target RNA cleavage events induced by the herpes simplex virus virion host shutoff protein.Disruption of virion host shutoff activity improves the immunogenicity and protective capacity of a replication-incompetent herpes simplex virus type 1 vaccine strain.Global mRNA degradation during lytic gammaherpesvirus infection contributes to establishment of viral latency.B7 costimulation molecules encoded by replication-defective, vhs-deficient HSV-1 improve vaccine-induced protection against corneal diseaseThe virion host shutoff endonuclease (UL41) of herpes simplex virus interacts with the cellular cap-binding complex eIF4F.Multiplex sequencing of seven ocular herpes simplex virus type-1 genomes: phylogeny, sequence variability, and SNP distributionTherapeutic immunization with a virion host shutoff-defective, replication-incompetent herpes simplex virus type 1 strain limits recurrent herpetic ocular infectionHerpes simplex virus type 1 origins of DNA replication play no role in the regulation of flanking promoters.Varicella-zoster virus (VZV) ORF17 protein induces RNA cleavage and is critical for replication of VZV at 37 degrees C but not 33 degrees C.mRNA degradation by the virion host shutoff (Vhs) protein of herpes simplex virus: genetic and biochemical evidence that Vhs is a nuclease.A subpopulation of tegument protein vhs localizes to detergent-insoluble lipid rafts in herpes simplex virus-infected cells.Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.Oncolytic herpes simplex virus 1 encoding 15-prostaglandin dehydrogenase mitigates immune suppression and reduces ectopic primary and metastatic breast cancer in mice.Herpes simplex virus ICP27 is required for virus-induced stabilization of the ARE-containing IEX-1 mRNA encoded by the human IER3 geneThe virion host shutoff protein of herpes simplex virus 1 blocks the replication-independent activation of NF-κB in dendritic cells in the absence of type I interferon signaling.Herpes simplex virus virion host shutoff protein: immune evasion mediated by a viral RNase?Functional genomics reveals an essential and specific role for Stat1 in protection of the central nervous system following herpes simplex virus corneal infectionHost shutoff during productive Epstein-Barr virus infection is mediated by BGLF5 and may contribute to immune evasion.Specific phenotypic restoration of an attenuated virus by knockout of a host resistance geneHerpes simplex virus type 2 virion host shutoff protein regulates alpha/beta interferon but not adaptive immune responses during primary infection in vivo.Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesisExpression and function of the equine herpesvirus 1 virion-associated host shutoff homolog.Recurrent herpetic stromal keratitis in mice: a model for studying human HSK.Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.
P2860
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P2860
Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@ast
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@en
type
label
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@ast
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@en
prefLabel
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@ast
Role of the virion host shutof ...... 1 in latency and pathogenesis.
@en
P2860
P1433
P1476
Role of the virion host shutof ...... 1 in latency and pathogenesis
@en
P2093
P2860
P304
P407
P577
1995-11-01T00:00:00Z