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Interpreting physicochemical experimental data sets.Development of novel ionic liquid-based microemulsion formulation for dermal delivery of 5-Fluorouracil.Biorelevant pK(a) (37 °C) predicted from the 2D structure of the molecule and its pK(a) at 25 °C.Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic Profiles of Oral Extended Release Methylphenidate Products in AdultsHow cocrystals of weakly basic drugs and acidic coformers might modulate solubility and stability.Population-based mechanistic prediction of oral drug absorptionGastric emptying of non-disintegrating solid drug delivery systems in fasted state: relevance to drug dissolution.Overview of drug product development.Development of Methods for the Determination of pKa Values.Microenvironmental pH-modification to improve dissolution behavior and oral absorption for drugs with pH-dependent solubility.Small Volume Dissolution Testing as a Powerful Method during Pharmaceutical Development.Intestinal solubility and absorption of poorly water soluble compounds: predictions, challenges and solutions.Formulation, characterization and permeability study of nano particles of lipo-endomorphin-1 for oral delivery.Enhanced acyclovir delivery using w/o type microemulsion: preclinical assessment of antiviral activity using murine model of zosteriform cutaneous HSV-1 infection.Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides.Solubility of pioglitazone hydrochloride in binary and ternary mixtures of water, propylene glycol, and polyethylene glycols 200, 400, and 600 at 298.2 kEffect of 2-hydroxypropyl-β-cyclodextrin on solubility of sparingly soluble drug derivatives of anthranilic acid.A potent preparation method combining neutralization with microfluidization for rebamipide nanosuspensions and its in vivo evaluation.SAMPL4, a blind challenge for computational solvation free energies: the compounds considered.Improving glyburide solubility and dissolution by complexation with hydroxybutenyl-beta-cyclodextrin.Niosomes for oral delivery of nateglinide: in situ-in vivo correlation.The absorption kinetics of ketoconazole plays a major role in explaining the reported variability in the level of interaction with midazolam: Interplay between formulation and inhibition of gut wall and liver metabolism.Understanding the Differences Between Cocrystal and Salt Aqueous Solubilities.Hydrosoluble benzo[e]pyridoindolones as potent inhibitors of aurora kinases.A mechanistic pharmacokinetic model to assess modified oral drug bioavailability post bariatric surgery in morbidly obese patients: interplay between CYP3A gut wall metabolism, permeability and dissolution
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Solubility of sparingly-soluble ionizable drugs.
@en
type
label
Solubility of sparingly-soluble ionizable drugs.
@en
prefLabel
Solubility of sparingly-soluble ionizable drugs.
@en
P1476
Solubility of sparingly-soluble ionizable drugs.
@en
P2093
Alex Avdeef
P304
P356
10.1016/J.ADDR.2007.05.008
P407
P577
2007-05-29T00:00:00Z