Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin.
about
Regulation of human endothelial cell focal adhesion sites and migration by cGMP-dependent protein kinase IPaxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeletonLeupaxin is a critical adaptor protein in the adhesion zone of the osteoclastRNF5, a RING finger protein that regulates cell motility by targeting paxillin ubiquitination and altered localizationLIM domain-containing adaptor, leupaxin, localizes in focal adhesion and suppresses the integrin-induced tyrosine phosphorylation of paxillinLeupaxin is similar to paxillin in focal adhesion targeting and tyrosine phosphorylation but has distinct roles in cell adhesion and spreading.Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathwayCoupling of PAK-interacting exchange factor PIX to GIT1 promotes focal complex disassemblyA truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylationCofilin phosphorylation by protein kinase testicular protein kinase 1 and its role in integrin-mediated actin reorganization and focal adhesion formationPaxillin comes of agePaxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling.Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesionPost-translational modification-regulated leukocyte adhesion and migrationThe PXL1 gene of Saccharomyces cerevisiae encodes a paxillin-like protein functioning in polarized cell growth.Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PESTAltered focal adhesion regulation correlates with cardiomyopathy in mice expressing constitutively active rac1Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes suggests distinct roles in the cytoskeleton and in nIntegrin-linked kinase (ILK) binding to paxillin LD1 motif regulates ILK localization to focal adhesionsMultiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillinLinkage of caspase-mediated degradation of paxillin to apoptosis in Ba/F3 murine pro-B lymphocytesThe adaptor protein paxillin is essential for normal development in the mouse and is a critical transducer of fibronectin signalingSrc and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness.Paxillin: a focal adhesion-associated adaptor protein.Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells.The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.Interaction of paxillin with p21-activated Kinase (PAK). Association of paxillin alpha with the kinase-inactive and the Cdc42-activated forms of PAK3.GWAS meets microarray: are the results of genome-wide association studies and gene-expression profiling consistent? Prostate cancer as an example.Phosphorylation of paxillin at threonine 538 by PKCdelta regulates LFA1-mediated adhesion of lymphoid cells.Molecular dissection of actopaxin-integrin-linked kinase-Paxillin interactions and their role in subcellular localization.Constitutive p21-activated kinase (PAK) activation in breast cancer cells as a result of mislocalization of PAK to focal adhesionsSerine phosphorylation regulates paxillin turnover during cell migration.IP-10 inhibits epidermal growth factor-induced motility by decreasing epidermal growth factor receptor-mediated calpain activity.Hsp27 inhibits sublethal, Src-mediated renal epithelial cell injury.Dictyostelium discoideum paxillin regulates actin-based processes.Differential requirement for MEK Partner 1 in DU145 prostate cancer cell migration.The importance of podocyte adhesion for a healthy glomerulus.Paxillin null embryonic stem cells are impaired in cell spreading and tyrosine phosphorylation of focal adhesion kinase.Involvement of the paxillin pathway in JB6 Cl41 cell transformation.Expression of the urokinase receptor regulates focal adhesion assembly and cell migration in adenoid cystic carcinoma cells.
P2860
Q22254250-6A759E6C-3DCA-4A8B-9AC3-D95EE4C4C7BAQ22254255-1247C07B-0607-4FEF-AF30-12D0367CE857Q24299233-95FADF72-0479-4CA7-8463-CF81F10BC45DQ24308703-77C8ECB6-88A6-4157-8398-491E06801B1BQ24317625-2FEB6D71-E2F0-4C14-9C02-069469F2FE97Q24319896-E5B0D5B0-4F19-4DF4-8059-C71EFE2BAF47Q24524132-D7CD238D-E1D9-42F0-A350-34653C232F38Q24552051-4695D99A-8575-4649-97FF-3DCA0CFD5667Q24601280-53356544-F323-4664-A5C6-A772C686ED1EQ24632940-EA27CF9A-1CD7-4AEE-AF6C-3C618B89682BQ24657852-E0BFB6CC-7579-49A5-AD11-A587E44058E8Q24682031-6B31F4D4-005A-42DE-97A5-A6A841EA34B5Q24685749-429D6D25-6BAF-4130-8FFD-2A17940B6A28Q26753208-5F9B9DCA-5361-4466-942C-A026AE826006Q27934723-68918522-165B-4D04-A2DE-A5B32636EDF1Q28139276-E0C00B4A-4081-4DC0-AD3B-4C654E8A8994Q28140811-0C7BE6A6-FDAA-473C-880D-E92465954EFEQ28144167-BCE3DEA1-35DE-47E1-B3B6-4D0BF4D72E4AQ28212649-79536CC3-1759-4007-9DFD-2A4ACCDB43EAQ28363290-13562432-D548-4D95-AD67-9C105A2FFF08Q28508545-44B746F5-63A8-457B-AF5E-8F6F5670CACAQ28589349-C5375C90-80AF-44F6-9927-77C990461AD3Q30160185-0A3E0499-AB24-4F50-8B76-B678481C1B2CQ30167845-E1BC6618-9F10-4301-A1B1-B5FA0AC9BFAAQ30175229-E111A5CB-DB3B-4997-B9FB-4832F206AB31Q30578832-A5268126-F6DA-429A-81CB-D56B043AB6A4Q31628373-A4699DAA-146D-4846-A296-78FD2BDE6DBDQ33490113-F2733F24-F571-442D-99EE-236C2E8C4EF7Q33803975-556D27BC-E7DA-42FC-91D5-169A642F07B4Q34100459-DC8B50A7-AC29-4FAC-AA09-C7E27AF99F45Q34360278-26F8D28F-52F8-43A0-88B1-B6D808568649Q35171946-FD0D291B-42C9-45A8-8812-91EE05DF42FCQ36382107-57AE3D38-958D-4DA8-A864-3BC98DC164E6Q37337324-775F49B5-C8EB-4535-9DB9-3F3CCC1A34A9Q37345269-9E6DBE28-C26A-4A6C-8937-61127CF5FDE9Q37458788-79860959-4576-4667-9CC0-DAD1007FC99DQ38263509-18D88BE5-FF3C-438B-B055-C2B42EBF589CQ38292943-A34202F8-7575-40C4-9FDA-C1CFBAFAF7A6Q40272691-B9A54D11-9AB1-45C1-8079-FFF9FD101CACQ40496993-06F9F0F4-7A92-4CD4-BCBD-BEED45C041D2
P2860
Serine and threonine phosphorylation of the paxillin LIM domains regulates paxillin focal adhesion localization and cell adhesion to fibronectin.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Serine and threonine phosphory ...... cell adhesion to fibronectin.
@en
type
label
Serine and threonine phosphory ...... cell adhesion to fibronectin.
@en
prefLabel
Serine and threonine phosphory ...... cell adhesion to fibronectin.
@en
P2093
P2860
P356
P1476
Serine and threonine phosphory ...... cell adhesion to fibronectin.
@en
P2093
C E Turner
J A Perrotta
P2860
P304
P356
10.1091/MBC.9.7.1803
P577
1998-07-01T00:00:00Z