The T-antigen-binding domain of the simian virus 40 core origin of replication.
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Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor AntigenGeometry of the simian virus 40 large tumor antigen-DNA complex as probed by protease digestionTopoisomerase I associates specifically with simian virus 40 large-T-antigen double hexamer-origin complexesConformational changes in simian virus 40 rearranged regulatory regions: effects of the 21-base-pair promoters and their location.The E1 initiator recognizes multiple overlapping sites in the papillomavirus origin of DNA replication.Spacing is crucial for coordination of domain functions within the simian virus 40 core origin of replication.Sequence requirements for plasmid nuclear import.Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplicationSimian virus 40 large tumor antigen requires three core replication origin domains for DNA unwinding and replication in vitroATP-dependent formation of a specialized nucleoprotein structure by simian virus 40 (SV40) large tumor antigen at the SV40 replication origin.The structure of SV40 large T hexameric helicase in complex with AT-rich origin DNA.Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replicationEffects of the simian virus 40 origin of replication on transcription from the human immunodeficiency virus type 1 promoterReplication of simian virus 40 origin-containing DNA during infection with a recombinant Autographa californica multiple nuclear polyhedrosis virus expressing large T antigen.Purification of the simian virus 40 (SV40) T antigen DNA-binding domain and characterization of its interactions with the SV40 origin.The N-terminal side of the origin-binding domain of simian virus 40 large T antigen is involved in A/T untwisting.Quantitative analysis of the binding of simian virus 40 large T antigen to DNA.Localized melting and structural changes in the SV40 origin of replication induced by T-antigen.Relationship among location of T-antigen-induced DNA distortion, auxiliary sequences, and DNA replication efficiencyBiochemical analysis of mutants with changes in the origin-binding domain of simian virus 40 tumor antigencdc2 phosphorylation of threonine 124 activates the origin-unwinding functions of simian virus 40 T antigenDifferential induction of structural changes in the simian virus 40 origin of replication by T antigen.Initiation of simian virus 40 DNA synthesis in vitro.Cooperative assembly of simian virus 40 T-antigen hexamers on functional halves of the replication origin.Asp-286----Asn-286 in polyomavirus large T antigen relaxes the specificity of binding to the polyomavirus origin.Analysis of origin of DNA replication of human papovavirus BK.Identification of critical elements within the JC virus DNA replication originThermally inactivated simian virus 40 tsA58 mutant T antigen cannot initiate viral DNA replication in vitroThree domains in the simian virus 40 core origin orchestrate the binding, melting, and DNA helicase activities of T antigen.Four major sequence elements of simian virus 40 large T antigen coordinate its specific and nonspecific DNA binding.Topoisomerase I sites cluster asymmetrically at the ends of the simian virus 40 core origin of replication.Requirements for species-specific papovavirus DNA replication.A 67-base-pair segment from the Ori-S region of herpes simplex virus type 1 encodes origin functionATP enhances the binding of simian virus 40 large T antigen to the origin of replication.Nonspecific double-stranded DNA binding activity of simian virus 40 large T antigen is involved in melting and unwinding of the origin.Escherichia coli replication terminator protein impedes simian virus 40 (SV40) DNA replication fork movement and SV40 large tumor antigen helicase activity in vitro at a prokaryotic terminus sequence.ATP stimulates the binding of simian virus 40 (SV40) large tumor antigen to the SV40 origin of replication.O6-methylguanine in the SV40 origin of replication inhibits binding but increases unwinding by viral large T antigen.Recognition mechanisms in the synthesis of animal virus DNA.Sequence requirements for the assembly of simian virus 40 T antigen and the T-antigen origin binding domain on the viral core origin of replication.
P2860
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P2860
The T-antigen-binding domain of the simian virus 40 core origin of replication.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
The T-antigen-binding domain of the simian virus 40 core origin of replication.
@en
type
label
The T-antigen-binding domain of the simian virus 40 core origin of replication.
@en
prefLabel
The T-antigen-binding domain of the simian virus 40 core origin of replication.
@en
P2093
P2860
P1433
P1476
The T-antigen-binding domain of the simian virus 40 core origin of replication.
@en
P2093
P2860
P304
P407
P577
1987-07-01T00:00:00Z