Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs. - Wikidata - awgldk - TriplyDB

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

http://www.wikidata.org/entity/Q36891023

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Animal Models of Cystic Fibrosis Pathology: Phenotypic Parallels and Divergences Current progress of genetically engineered pig models for biomedical research Origins of cystic fibrosis lung disease Precision Genomic Medicine in Cystic Fibrosis Immunohistochemical detection of arginase-I expression in formalin-fixed lung and other tissues A functional anatomic defect of the cystic fibrosis airway.Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass.Animal models of gastrointestinal and liver diseases. Animal models of cystic fibrosis: gastrointestinal, pancreatic, and hepatobiliary disease and pathophysiology.Ferret and pig models of cystic fibrosis: prospects and promise for gene therapy.Hybrid nonviral/viral vector systems for improved piggyBac DNA transposon in vivo delivery Porcine models of digestive disease: the future of large animal translational research.Computed Tomography (CT) Scanning Facilitates Early Identification of Neonatal Cystic Fibrosis Piglets Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutation Quantitative proteomics reveals an altered cystic fibrosis in vitro bronchial epithelial secretome Partial Restoration of CFTR Function in cftr-Null Mice following Targeted Cell Replacement Therapy.Growth deficits in cystic fibrosis mice begin in utero prior to IGF-1 reduction.Pancreatic pathophysiology in cystic fibrosis.Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense.Human, Pig, and Mouse Interferon-Induced Transmembrane Proteins Partially Restrict Pseudotyped Lentiviral Vectors.Airway acidification initiates host defense abnormalities in cystic fibrosis mice.Lessons learned from the cystic fibrosis pig.A novel culture system for adult porcine intestinal crypts Lentiviral-mediated phenotypic correction of cystic fibrosis pigs.CFTR gene transfer with AAV improves early cystic fibrosis pig phenotypes Anchored PDE4 regulates chloride conductance in wild-type and ΔF508-CFTR human airway epithelia.Identification of the MUC2 Promoter as a Strong Promoter for Intestinal Gene Expression through Generation of Transgenic Quail Expressing GFP in Gut Epithelial Cells Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets.Does epithelial sodium channel hyperactivity contribute to cystic fibrosis lung disease?Genetically modified pigs to model human diseases.Anatomy and bronchoscopy of the porcine lung. A model for translational respiratory medicine.Modeling the lung: Design and development of tissue engineered macro- and micro-physiologic lung models for research use.Cystic fibrosis genetics: from molecular understanding to clinical application.Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies.Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models.Simple and reproducible approaches for the collection of select porcine ganglia.Postnatal airway growth in cystic fibrosis piglets.Genetic medicines for CF: Hype versus reality.Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.The CF gastrointestinal microbiome: Structure and clinical impact.

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P2860

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

http://www.wikidata.org/entity/Q36891023

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

@en

type

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Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

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Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

@en

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Journal of Clinical Investigation

P1476

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs.

@en

P2093

Christine Wohlford-Lenane

http://www.w3.org/2001/XMLSchema#string

Drake C Bouzek

http://www.w3.org/2001/XMLSchema#string

Emma E Hornick

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Eugene H Chang

http://www.w3.org/2001/XMLSchema#string

George A Nelson

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James D McMenimen

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Jeng-Haur Chen

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Katrina L Bogan

http://www.w3.org/2001/XMLSchema#string

Mark J Hoegger

http://www.w3.org/2001/XMLSchema#string

Melissa S Samuel

http://www.w3.org/2001/XMLSchema#string

P2860

Generation of cloned transgenic pigs rich in omega-3 fatty acids

Relative contribution of genetic and nongenetic modifiers to intestinal obstruction in cystic fibrosis.

Cystic fibrosis

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium

Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine.

Pathology of gastrointestinal organs in a porcine model of cystic fibrosis.

Pharmacological correction of a defect in PPAR-gamma signaling ameliorates disease severity in Cftr-deficient mice.

Issues in the management of simple and complex meconium ileus.

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth.

P304

2685-2693

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scholarly article

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10.1172/JCI68867

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P433

6

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123

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David Meyerholz

Randall S. Prather

Alejandro A Pezzulo

Mahmoud H Abou Alaiwa

Leah R Reznikov

Lynda S Ostedgaard

P577

2013-05-08T00:00:00Z

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23676501

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cystic fibrosis

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3668832

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