A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.
about
Molecular insights into the progression of crystalline silica-induced pulmonary toxicity in ratsZeGlobalTox: An Innovative Approach to Address Organ Drug Toxicity Using Zebrafish.Current and future applications of toxicogenomics: Results summary of a survey from the HESI Genomics State of Science SubcommitteeThe evolution of bioinformatics in toxicology: advancing toxicogenomicsA trichostatin A expression signature identified by TempO-Seq targeted whole transcriptome profilingVariations at a quantitative trait locus (QTL) affect development of behavior in lead-exposed Drosophila melanogaster.Human skin-derived stem cells as a novel cell source for in vitro hepatotoxicity screening of pharmaceuticals.Genetical toxicogenomics in Drosophila identifies master-modulatory loci that are regulated by developmental exposure to leadEffects of pharmaceuticals and other active chemicals at biological targets: mechanisms, interactions, and integration into PB-PK/PD models.Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?The impact of assay technology as applied to safety assessment in reducing compound attrition in drug discovery.A decade of toxicogenomic research and its contribution to toxicological science.On-target and off-target-based toxicologic effects.Safety biomarkers in preclinical development: translational potential.The future of safety science is happening now: The modernization of the benefit-risk paradigm.Toxicogenomic module associations with pathogenesis: a network-based approach to understanding drug toxicity.Toxicogenomic analysis of a sustained release local anesthetic delivery system.The liver toxicity biomarker study phase I: markers for the effects of tolcapone or entacapone.Whole genome microarray analysis of neural progenitor C17.2 cells during differentiation and validation of 30 neural mRNA biomarkers for estimation of developmental neurotoxicity.
P2860
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P2860
A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.
@en
type
label
A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.
@en
prefLabel
A retrospective analysis of toxicogenomics in the safety assessment of drug candidates.
@en
P2093
P2860
P1476
A retrospective analysis of toxicogenomics in the safety assessment of drug candidates
@en
P2093
Amy Truong
Bruce D Car
David M Nelson
Donna M Dambach
Lois D Lehman-McKeeman
Shen-Jue Chen
Vasanthi Bhaskaran
P2860
P304
P356
10.1080/01926230701419063
P407
P577
2007-08-01T00:00:00Z