Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients. - Wikidata - awgldk - TriplyDB

Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

http://www.wikidata.org/entity/Q36906186

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Pharmacogenetic studies update in type 2 diabetes mellitus Pharmacogenetics in type 2 diabetes: influence on response to oral hypoglycemic agents Coexpression of the type 2 diabetes susceptibility gene variants KCNJ11 E23K and ABCC8 S1369A alter the ATP and sulfonylurea sensitivities of the ATP-sensitive K(+) channel.KCNJ11: Genetic Polymorphisms and Risk of Diabetes Mellitus Pharmacogenomics in diabetes mellitus: insights into drug action and drug discovery Personalized medicine in Type 2 Diabetes Pharmacogenomics in type 2 diabetes: oral antidiabetic drugs.Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.Genetics of type 2 diabetes: insights into the pathogenesis and its clinical application.KCNJ11, ABCC8 and TCF7L2 polymorphisms and the response to sulfonylurea treatment in patients with type 2 diabetes: a bioinformatics assessment.Large-scale pharmacogenomic study of sulfonylureas and the QT, JT and QRS intervals: CHARGE Pharmacogenomics Working Group.Sulfonylurea pharmacogenomics in Type 2 diabetes: the influence of drug target and diabetes risk polymorphisms.Pharmacogenomics of oral antidiabetic medications: current data and pharmacoepigenomic perspective.Clinical translation of genetic predictors for type 2 diabetes.Pharmacogenetics of Anti-Diabetes Drugs.Pharmacogenetics in type 2 diabetes: potential implications for clinical practice Monogenic models: what have the single gene disorders taught us?Pharmacogenomics in type II diabetes mellitus management: Steps toward personalized medicine.Genetic architecture of type 2 diabetes: recent progress and clinical implications CYP2C93 variant is associated with antidiabetes efficacy of gliclazide in Chinese type 2 diabetes patients The clinical application of genetic testing in type 2 diabetes: a patient and physician survey.Pharmacogenetics of oral antidiabetic drugs.Pharmacogenetics and personalized treatment of type 2 diabetes Polymorphisms of the KCNQ1 gene are associated with the therapeutic responses of sulfonylureas in Chinese patients with type 2 diabetes.The pharmacogenetics of type 2 diabetes: a systematic review.Genetic susceptibility to type 2 diabetes and implications for therapy.The genetics of type 2 diabetes: what have we learned from GWAS?Type 2 diabetes and obesity: genomics and the clinic.The molecular genetics of sulfonylurea receptors in the pathogenesis and treatment of insulin secretory disorders and type 2 diabetes.The genetics of type 2 diabetes and its clinical relevance.Genetics of type 2 diabetes and potential clinical implications.The role of pharmacogenetics in drug disposition and response of oral glucose-lowering drugs.Stratified medicine for the use of antidiabetic medication in treatment of type II diabetes and cancer: where do we go from here?Genetics of drug response in type 2 diabetes.Using Personalized Medicine in the Management of Diabetes Mellitus.Genetic markers predicting sulphonylurea treatment outcomes in type 2 diabetes patients: current evidence and challenges for clinical implementation.Pharmacogenetics in type 2 diabetes: precision medicine or discovery tool?Pharmacogenetic aspects of the treatment of Type 2 diabetes with the incretin effect enhancers.The Application of Genomics in Diabetes: Barriers to Discovery and Implementation.Association between TCF7L2 Genotype and Glycemic Control in Diabetic Patients Treated with Gliclazide.

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Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

http://www.wikidata.org/entity/Q36906186

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Guangyun Mao

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Houxun Xing

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Jinqui Yang

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Lirong Sun

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Qiang Li

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Weiqing Ma

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Xiaobin Wang

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Xiaowei Ren

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Xiping Xu

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P2860

Global prevalence of diabetes: estimates for the year 2000 and projections for 2030

Activating mutations in the ABCC8 gene in neonatal diabetes mellitus.

A rare mutation in ABCC8/SUR1 leading to altered ATP-sensitive K+ channel activity and beta-cell glucose sensing is associated with type 2 diabetes in adults.

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

Sequence variants in the sulfonylurea receptor (SUR) gene are associated with NIDDM in Caucasians.

Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.

Association studies of variants in the genes involved in pancreatic beta-cell function in type 2 diabetes in Japanese subjects.

Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action

A new era for Type 2 diabetes genetics

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