Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
about
Different prognostic impact of STK11 mutations in non-squamous non-small-cell lung cancer.BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implicationsEngineering ePTEN, an enhanced PTEN with increased tumor suppressor activities.The butterfly effect in cancer: a single base mutation can remodel the cell.A phosphoproteomic screen demonstrates differential dependence on HER3 for MAP kinase pathway activation by distinct PIK3CA mutations.Autism Linked to Increased Oncogene Mutations but Decreased Cancer Rate.Mutant PIK3CA Induces EMT in a Cell Type Specific MannerOverexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor-negative breast cancer.HER2 missense mutations have distinct effects on oncogenic signaling and migration.The combinatorial activation of the PI3K and Ras/MAPK pathways is sufficient for aggressive tumor formation, while individual pathway activation supports cell persistence.Mutations in PIK3CA sensitize breast cancer cells to physiologic levels of aspirin3-Phosphoinositide-dependent protein kinase-1 as an emerging target in the management of breast cancer.Emerging role of the KRAS-PDK1 axis in pancreatic cancer.Engineering PTEN function: membrane association and activity.PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity.A new class of cancer-associated PTEN mutations defined by membrane translocation defects.Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis.
P2860
Q27853286-4C73389B-D816-4394-9CB4-B3591C2D5BC2Q28543370-44E35E7B-90D6-46D3-BF20-DC1F30314CA5Q33854076-AD4673E8-583B-4E3A-8A5D-8DA033B8B327Q35037970-9A6B729C-5CB9-494E-9633-37A07BDE3308Q35155664-1D71E112-98A2-4C8E-8074-DF01D20AFD55Q35943062-46A53F42-E0D4-4211-B241-69A0843D3E7EQ36219957-B5960E84-6A9C-4097-ACA6-25AC922A5FF8Q36298086-318C89A0-A253-4FF6-AECD-29CC0D45DC70Q36300320-49D5610B-39E6-474A-B9C3-8077F2D0A269Q36546319-1B220781-73C2-4141-AE15-E443C817EAD2Q36678527-FE60A803-B83F-4761-A381-47ADFD464F32Q37167731-C89D76D6-7486-4A52-B5D5-CD736437A927Q38242805-2F3008E7-A8A2-4197-BE2C-A436E8CB6E54Q38275377-782E82B3-A053-428A-9B6D-9CEC51B0C595Q38716747-8CEE0040-E140-4E3B-9A83-DCC01B72034FQ38952567-A9154BCD-E129-4BAA-91C2-8C536B513EFCQ41472845-047E5246-05D2-41AA-9CB1-D1A4A28840C0
P2860
Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Single copies of mutant KRAS a ...... lls to induce tumor formation.
@en
type
label
Single copies of mutant KRAS a ...... lls to induce tumor formation.
@en
prefLabel
Single copies of mutant KRAS a ...... lls to induce tumor formation.
@en
P2093
P2860
P1433
P1476
Single copies of mutant KRAS a ...... lls to induce tumor formation.
@en
P2093
Abde M Abukhdeir
Akinobu Ota
Ben Ho Park
Brian G Blair
D Marc Rosen
Danijela Jelovac
Grace M Wang
Hiroyuki Konishi
Hong Yuen Wong
John P Gustin
P2860
P304
P356
10.1158/0008-5472.CAN-12-1578
P407
P577
2013-04-11T00:00:00Z