Notch3 functions as a tumor suppressor by controlling cellular senescence
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Notch signaling in prostate cancer: refining a therapeutic opportunityEvasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.From fly wings to targeted cancer therapies: a centennial for notch signalingEpigenetics in liver disease: from biology to therapeuticsNOTCH1 mediates a switch between two distinct secretomes during senescence.Notch3 overexpression enhances progression and chemoresistance of urothelial carcinoma.Characterization of novel markers of senescence and their prognostic potential in cancer.Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors.Notch3 overexpression promotes anoikis resistance in epithelial ovarian cancer via upregulation of COL4A2.Hes1: a key role in stemness, metastasis and multidrug resistance.Notch3 overexpression causes arrest of cell cycle progression by inducing Cdh1 expression in human breast cancer cells.BRCA1 is a key regulator of breast differentiation through activation of Notch signalling with implications for anti-endocrine treatment of breast cancers.Notch3 inhibits epithelial-mesenchymal transition by activating Kibra-mediated Hippo/YAP signaling in breast cancer epithelial cells.Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells.Developmental pathways activated in melanocytes and melanoma.The opposing roles of NOTCH signalling in head and neck cancer: a mini review.Vinblastine and antihelmintic mebendazole potentiate temozolomide in resistant gliomas.Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.Notch3 expression correlates with thyroid cancer differentiation, induces apoptosis, and predicts disease prognosis.Notch promotes tumor metastasis in a prostate-specific Pten-null mouse modelNotch signaling molecules as prognostic biomarkers for non-small cell lung cancer.Aberrant expression of Notch1, HES1, and DTX1 genes in glioblastoma formalin-fixed paraffin-embedded tissues.Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype, tumor cell lines and normal pituitariesCellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities.Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury.RNA-seq transcriptome analysis of formalin fixed, paraffin-embedded canine meningioma.Notch3 Maintains Luminal Phenotype and Suppresses Tumorigenesis and Metastasis of Breast Cancer via Trans-Activating Estrogen Receptor-α.Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma.IL6 blockade potentiates the anti-tumor effects of γ-secretase inhibitors in Notch3-expressing breast cancer.DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma.Detection of Senescent Cells by Extracellular Markers Using a Flow Cytometry-Based Approach.CD36 initiates the secretory phenotype during the establishment of cellular senescenceCancer Cells Exploit Notch Signaling to Redefine a Supportive Cytokine Milieu
P2860
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P2860
Notch3 functions as a tumor suppressor by controlling cellular senescence
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Notch3 functions as a tumor suppressor by controlling cellular senescence
@en
type
label
Notch3 functions as a tumor suppressor by controlling cellular senescence
@en
prefLabel
Notch3 functions as a tumor suppressor by controlling cellular senescence
@en
P2093
P2860
P1433
P1476
Notch3 functions as a tumor suppressor by controlling cellular senescence
@en
P2093
P2860
P304
P356
10.1158/0008-5472.CAN-12-3902
P407
P577
2013-04-22T00:00:00Z