A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells
about
Sphingosine kinase 1 in cancer.Inhibition of multiple protective signaling pathways and Ad.5/3 delivery enhances mda-7/IL-24 therapy of malignant gliomaLong-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.Extracellular sphingosine-1-phosphate: a novel actor in human glioblastoma stem cell survivalSphingosine kinase 1 as an anticancer therapeutic target.Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer.Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastomaA sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagyProteasome inhibition with bortezomib induces cell death in GBM stem-like cells and temozolomide-resistant glioma cell lines, but stimulates GBM stem-like cells' VEGF production and angiogenesisExpression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme.Interference with distinct steps of sphingolipid synthesis and signaling attenuates proliferation of U87MG glioma cells.Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism.Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino-demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging.Imaging colon cancer response following treatment with AZD1152: a preclinical analysis of [18F]fluoro-2-deoxyglucose and 3'-deoxy-3'-[18F]fluorothymidine imagingThe role of sphingosine kinase isoforms and receptors S1P1, S1P2, S1P3, and S1P5 in primary, secondary, and recurrent glioblastomas.Long noncoding RNA MALAT1 knockdown reverses chemoresistance to temozolomide via promoting microRNA-101 in glioblastoma.New extracellular factors in glioblastoma multiforme development: neurotensin, growth differentiation factor-15, sphingosine-1-phosphate and cytomegalovirus infection.
P2860
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P2860
A sphingosine kinase inhibitor induces cell death in temozolomide resistant glioblastoma cells
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
A sphingosine kinase inhibitor ...... e resistant glioblastoma cells
@en
type
label
A sphingosine kinase inhibitor ...... e resistant glioblastoma cells
@en
prefLabel
A sphingosine kinase inhibitor ...... e resistant glioblastoma cells
@en
P2093
P2860
P1476
A sphingosine kinase inhibitor ...... e resistant glioblastoma cells
@en
P2093
Meryem Bektas
Stewart P Johnson
William E Poe
P2860
P2888
P304
P356
10.1007/S00280-009-1063-0
P577
2009-07-12T00:00:00Z