Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity. - Wikidata - awgldk - TriplyDB

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.

Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.

http://www.wikidata.org/entity/Q36907736

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Potential roles of microglial cell progranulin in HIV-associated CNS pathologies and neurocognitive impairment Progranulin: at the interface of neurodegenerative and metabolic diseases PGRN induces impaired insulin sensitivity and defective autophagy in hepatic insulin resistance Granulin exacerbates lupus nephritis via enhancing macrophage M2b polarization.Serum progranulin levels are elevated in dermatomyositis patients with acute interstitial lung disease, predicting prognosis Progranulin facilitates conversion and function of regulatory T cells under inflammatory conditions.The role of PGRN in musculoskeletal development and disease.Progranulin Is Associated with Disease Activity in Patients with Rheumatoid Arthritis.Administration of progranulin (PGRN) triggers ER stress and impairs insulin sensitivity via PERK-eIF2α-dependent manner.Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner Identification of biological pathways regulated by PGRN and GRN peptide treatments using transcriptome analysis.Progranulin: A key player in autoimmune diseases.Contribution of Progranulin to Protective Lung Immunity During Bacterial Pneumonia.Progranulin Plays a Central Role in Host Defense during Sepsis by Promoting Macrophage Recruitment.Stability of Progranulin Under Pre-Analytical Conditions in Serum and Cerebrospinal Fluid.Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice.PGRN protects against colitis progression in mice in an IL-10 and TNFR2 dependent manner.Serum progranulin levels in Hispanic rheumatoid arthritis patients treated with TNF antagonists: a prospective, observational study.Identification of a subnuclear body involved in sequence-specific cytokine RNA processing.Acute-phase proteins in prediction of preeclampsia in patients with abnormal midtrimester uterine Doppler velocimetry.

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Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity.

http://www.wikidata.org/entity/Q36907736

description

2012 nî lūn-bûn

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Serum progranulin levels are e ...... , reflecting disease activity.

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Serum progranulin levels are e ...... , reflecting disease activity.

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Arthritis Research and Therapy

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Serum progranulin levels are e ...... , reflecting disease activity.

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Atsushi Tanaka

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Chikako Kiyohara

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Hiroaki Niiro

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Hiroki Mitoma

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Hiroshi Tsukamoto

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Koichi Akashi

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Masahiro Ayano

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Naoyasu Ueda

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Shun-ichiro Ohta

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Takahiko Horiuchi

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P2860

A Toll-like receptor recognizes bacterial DNA

Pathogen recognition and innate immunity

Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus

Proteinase 3 and neutrophil elastase enhance inflammation in mice by inactivating antiinflammatory progranulin.

Cellular localization of gene expression for progranulin.

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

CpG motifs in bacterial DNA and their immune effects.

The growth factor progranulin binds to TNF receptors and is therapeutic against inflammatory arthritis in mice.

Progranulin (granulin-epithelin precursor, PC-cell-derived growth factor, acrogranin) mediates tissue repair and tumorigenesis.

Immune complexes from SLE sera induce IL10 production from normal peripheral blood mononuclear cells by an FcgammaRII dependent mechanism: implications for a possible vicious cycle maintaining B cell hyperactivity in SLE.

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10.1186/AR4087

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6

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