Structure and acetyl-lysine recognition of the bromodomain.
about
In vitro nuclear interactome of the HIV-1 Tat proteinStructural implications for K5/K12-di-acetylated histone H4 recognition by the second bromodomain of BRD2A cooperative activation loop among SWI/SNF, gamma-H2AX and H3 acetylation for DNA double-strand break repairPHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencingRecognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactionsStructural insights into recognition of acetylated histone ligands by the BRPF1 bromodomainBrd4 coactivates transcriptional activation of NF-kappaB via specific binding to acetylated RelAMolecular architecture of quartet MOZ/MORF histone acetyltransferase complexesPro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repressionThe role of human bromodomains in chromatin biology and gene transcriptionStructural insights into human KAP1 PHD finger-bromodomain and its role in gene silencingStructural genomics of histone tail recognitionRegulation of chromatin by histone modificationsComposition of the SAGA complex in plants and its role in controlling gene expression in response to abiotic stressesRegulation of glycolysis and gluconeogenesis by acetylation of PKM and PEPCKChromatin targeting drugs in cancer and immunityThe bromodomain: from epigenome reader to druggable targetProtein lysine acetylation by p300/CBPProtein lysine acylation and cysteine succination by intermediates of energy metabolismStructural Basis of Site-Specific Histone Recognition by the Bromodomains of Human Coactivators PCAF and CBP/p300Structures of the Dual Bromodomains of the P-TEFb-activating Protein Brd4 at Atomic ResolutionStructural Basis for Acetylated Histone H4 Recognition by the Human BRD2 BromodomainAcetylation regulates Cyclophilin A catalysis, immunosuppression and HIV isomerizationStructures of Metal-Substituted Human Histone Deacetylase 8 Provide Mechanistic Inferences on Biological Function,A Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in CardiomyocytesTwo surfaces on the histone chaperone Rtt106 mediate histone binding, replication, and silencingDiscovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual ScreeningDiscovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration AnalysisA noncanonical bromodomain in the AAA ATPase protein Yta7 directs chromosomal positioning and barrier chromatin activity.Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3A combination of H2A.Z and H4 acetylation recruits Brd2 to chromatin during transcriptional activationA Novel Phenanthridionone Based Scaffold As a Potential Inhibitor of the BRD2 Bromodomain: Crystal Structure of the ComplexMultivalent engagement of chromatin modifications by linked binding modulesHistone hypoacetylation-activated genes are repressed by acetyl-CoA- and chromatin-mediated mechanism.Chemical phylogenetics of histone deacetylases.Zebrafish brd2a and brd2b are paralogous members of the bromodomain-ET (BET) family of transcriptional coregulators that show structural and expression divergence.Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression.In vivo chromatin organization of mouse rod photoreceptors correlates with histone modificationsEpigenetic control of immunityGene expression profiling reveals large regulatory switches between succeeding stipe stages in Volvariella volvacea.
P2860
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P2860
Structure and acetyl-lysine recognition of the bromodomain.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Structure and acetyl-lysine recognition of the bromodomain.
@en
type
label
Structure and acetyl-lysine recognition of the bromodomain.
@en
prefLabel
Structure and acetyl-lysine recognition of the bromodomain.
@en
P2093
P2860
P356
P1433
P1476
Structure and acetyl-lysine recognition of the bromodomain.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210618
P407
P577
2007-08-01T00:00:00Z