Differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large T antigen encoded by simian virus 40-adenovirus 7 hybrid viruses.
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Protein phosphatase 2A dephosphorylates simian virus 40 large T antigen specifically at residues involved in regulation of DNA-binding activityRegulation of SV40 DNA replication by phosphorylation of T antigenThe abnormal location of cytoplasmic SV40 large T is not caused by failure to bind to DNA or to p53.Genetic analysis of polyomavirus large T nuclear localization: nuclear localization is required for productive association with pRb family members.Removal of serine phosphates from simian virus 40 large T antigen increases its ability to stimulate DNA replication in vitro but has no effect on ATPase and DNA bindingBiochemical characterization of phosphorylation site mutants of simian virus 40 large T antigen: evidence for interaction between amino- and carboxy-terminal domains.Mutations in the phosphorylation sites of simian virus 40 (SV40) T antigen alter its origin DNA-binding specificity for sites I or II and affect SV40 DNA replication activity.Polyomavirus large T antigen induces alterations in cytoplasmic signalling pathways involving Shc activation.Phosphorylation of simian virus 40 T antigen on Thr 124 selectively promotes double-hexamer formation on subfragments of the viral core origin.T-antigen kinase inhibits simian virus 40 DNA replication by phosphorylation of intact T antigen on serines 120 and 123.The E1 replication protein of bovine papillomavirus type 1 contains an extended nuclear localization signal that includes a p34cdc2 phosphorylation site.Analysis of simian virus 40 small t antigen-induced progression of rat F111 cells minimally transformed by large T antigen.Altered phosphorylation pattern of simian virus 40 T antigen expressed in insect cells by using a baculovirus vector.Phenotype-specific phosphorylation of simian virus 40 tsA mutant large T antigens in tsA N-type and A-type transformants.Effects of in vitro dephosphorylation on DNA-binding and DNA helicase activities of simian virus 40 large tumor antigen.Dimers and complexes with p53 are the prevalent oligomeric forms of a transforming nonkaryophilic T antigen of simian virus 40.Nuclear transport kinetics depend on phosphorylation-site-containing sequences flanking the karyophilic signal of the Simian virus 40 T-antigen.p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins.Different oligomeric forms of protein phosphatase 2A activate and inhibit simian virus 40 DNA replication.BK virus as a cofactor in the etiology of prostate cancer in its early stages.
P2860
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P2860
Differential phosphorylation of cytoplasmic and nuclear variants of simian virus 40 large T antigen encoded by simian virus 40-adenovirus 7 hybrid viruses.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Differential phosphorylation o ...... 0-adenovirus 7 hybrid viruses.
@en
type
label
Differential phosphorylation o ...... 0-adenovirus 7 hybrid viruses.
@en
prefLabel
Differential phosphorylation o ...... 0-adenovirus 7 hybrid viruses.
@en
P2093
P2860
P1433
P1476
Differential phosphorylation o ...... 0-adenovirus 7 hybrid viruses.
@en
P2093
J Schickedanz
K H Scheidtmann
R E Lanford
P2860
P304
P407
P577
1984-05-01T00:00:00Z