Demonstration in vitro that eucaryotic initiation factor 3 is active but that a cap-binding protein complex is inactive in poliovirus-infected HeLa cells
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The translation initiation factor eIF-4B contains an RNA-binding region that is distinct and independent from its ribonucleoprotein consensus sequenceMechanism and regulation of eukaryotic protein synthesisInhibition of translation in cells infected with a poliovirus 2Apro mutant correlates with phosphorylation of the alpha subunit of eucaryotic initiation factor 2TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4FCleavage of poly(A)-binding protein by enterovirus proteases concurrent with inhibition of translation in vitro.Eukaryotic initiation factor 3 is required for poliovirus 2A protease-induced cleavage of the p220 component of eukaryotic initiation factor 4F.Purification and partial characterization of poliovirus protease 2A by means of a functional assayClinical and experimental aspects of viral myocarditis.Coupled translation and replication of poliovirus RNA in vitro: synthesis of functional 3D polymerase and infectious virusRelationship of eukaryotic initiation factor 3 to poliovirus-induced p220 cleavage activityExpression of antisense RNA against initiation factor eIF-4E mRNA in HeLa cells results in lengthened cell division times, diminished translation rates, and reduced levels of both eIF-4E and the p220 component of eIF-4F.Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220.Evidence for the presence of an inhibitor on ribosomes in mouse L cells infected with mengovirus.The adenovirus tripartite leader may eliminate the requirement for cap-binding protein complex during translation initiationHuman rhinovirus 14 infection of HeLa cells results in the proteolytic cleavage of the p220 cap-binding complex subunit and inactivates globin mRNA translation in vitro.Poliovirus protease 3C (P3-7c) does not cleave P220 of the eucaryotic mRNA cap-binding protein complex.Restriction of translation of capped mRNA in vitro as a model for poliovirus-induced inhibition of host cell protein synthesis: relationship to p220 cleavageMonoclonal antibody-aided characterization of cellular p220 in uninfected and poliovirus-infected HeLa cells: subcellular distribution and identification of conformers.Poliovirus proteinase 2A induces cleavage of eucaryotic initiation factor 4F polypeptide p220.Proteinase trapping: screening for viral proteinase mutants by alpha complementation.Poliovirus protease does not mediate cleavage of the 220,000-Da component of the cap binding protein complexEukaryotic translation initiation factor 4G is targeted for proteolytic cleavage by caspase 3 during inhibition of translation in apoptotic cells.Initiation of protein synthesis in mammalian cellsCleavage of eukaryotic initiation factor eIF5B by enterovirus 3C proteases.Intracellular modifications induced by poliovirus reduce the requirement for structural motifs in the 5' noncoding region of the genome involved in internal initiation of protein synthesis.Proteolysis of the p220 component of the cap-binding protein complex is not sufficient for complete inhibition of host cell protein synthesis after poliovirus infection.
P2860
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P2860
Demonstration in vitro that eucaryotic initiation factor 3 is active but that a cap-binding protein complex is inactive in poliovirus-infected HeLa cells
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1984 nî lūn-bûn
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1984年の論文
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1984年論文
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1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
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1984年论文
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1984年论文
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1984年论文
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name
Demonstration in vitro that eu ...... poliovirus-infected HeLa cells
@en
type
label
Demonstration in vitro that eu ...... poliovirus-infected HeLa cells
@en
prefLabel
Demonstration in vitro that eu ...... poliovirus-infected HeLa cells
@en
P2093
P2860
P1433
P1476
Demonstration in vitro that eu ...... poliovirus-infected HeLa cells
@en
P2093
D Etchison
E Ehrenfeld
J W Hershey
N Sonenberg
P2860
P304
P407
P577
1984-09-01T00:00:00Z