The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice.
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Evolutionary silencing of the human elastase I gene (ELA1)Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreasThe DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse developmentMutagenesis in rodents using the L1 retrotransposonOrgan injury associated with extrathymic induction of immune tolerance in doubly transgenic mice.Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells.Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal-deletion mechanismBMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion.Pancreatic acinar cell-specific overexpression of group 1B phospholipase A2 exacerbates diet-induced obesity and insulin resistance in miceA 500-bp region, approximately 40 kb upstream of the human CYP19 (aromatase) gene, mediates placenta-specific expression in transgenic mice.Binding of a pancreatic nuclear protein is correlated with amylase enhancer activityAn mSin3A interaction domain links the transcriptional activity of KLF11 with its role in growth regulation.Analysis of the mouse protamine 1 promoter in transgenic miceExpression of the third member of the serum amyloid A gene family in mouse adipocytes.Tolerance in transgenic mice expressing class II major histocompatibility complex on pancreatic acinar cells.Use of transgenic mice to map cis-acting elements in the intestinal fatty acid binding protein gene (Fabpi) that control its cell lineage-specific and regional patterns of expression along the duodenal-colonic and crypt-villus axes of the gut epitheBinding sites for hepatocyte nuclear factor 3 beta or 3 gamma and pancreas transcription factor 1 are required for efficient expression of the gene encoding pancreatic alpha-amylase.Cooperation between elements of an organ-specific transcriptional enhancer in animalsA single element of the elastase I enhancer is sufficient to direct transcription selectively to the pancreas and gut.Distal regulatory elements from the mouse metallothionein locus stimulate gene expression in transgenic miceTransactivation of pancreas-specific gene sequences in somatic cell hybridsExocrine pancreas transcription factor 1 binds to a bipartite enhancer element and activates transcription of acinar genes.Muscle creatine kinase sequence elements regulating skeletal and cardiac muscle expression in transgenic miceThe muscle creatine kinase gene is regulated by multiple upstream elements, including a muscle-specific enhancerRegulated expression of a transfected human cardiac actin gene during differentiation of multipotential murine embryonal carcinoma cellsThe cell-specific elastase I enhancer comprises two domainsExpression from the transferrin gene promoter in transgenic miceA mouse oocyte-specific protein that binds to a region of mZP3 promoter responsible for oocyte-specific mZP3 gene expressionFunctional dissection of the lck proximal promoter.A C/EBP-binding site in the transferrin promoter is essential for expression in the liver but not the brain of transgenic mice.Interactions between the promoter and first intron are involved in transcriptional control of alpha 1(I) collagen gene expression.Promoter and enhancer elements from the rat elastase I gene function independently of each other and of heterologous enhancersInvolvement of autophagy in trypsinogen activation within the pancreatic acinar cellsBinary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.Introns increase transcriptional efficiency in transgenic mice.A cis-acting element and associated binding factor required for CNS expression of the Drosophila melanogaster dopa decarboxylase gene.Targeted integration of genes in Xenopus tropicalis.The Promoter and Multiple Enhancers of the pou4f3 Gene Regulate Expression in Inner Ear Hair Cells.Molecular analysis of the first intron in the bovine myostatin gene.Transcriptional autoregulation controls pancreatic Ptf1a expression during development and adulthood.
P2860
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P2860
The rat elastase I regulatory element is an enhancer that directs correct cell specificity and developmental onset of expression in transgenic mice.
description
1987 nî lūn-bûn
@nan
1987年の論文
@ja
1987年論文
@yue
1987年論文
@zh-hant
1987年論文
@zh-hk
1987年論文
@zh-mo
1987年論文
@zh-tw
1987年论文
@wuu
1987年论文
@zh
1987年论文
@zh-cn
name
The rat elastase I regulatory ...... expression in transgenic mice.
@en
type
label
The rat elastase I regulatory ...... expression in transgenic mice.
@en
prefLabel
The rat elastase I regulatory ...... expression in transgenic mice.
@en
P2093
P2860
P356
P1476
The rat elastase I regulatory ...... expression in transgenic mice.
@en
P2093
C J Quaife
D M Ornitz
R D Palmiter
R E Hammer
R J MacDonald
R L Brinster
P2860
P304
P356
10.1128/MCB.7.8.2956
P407
P577
1987-08-01T00:00:00Z