The role of Gas1 in embryonic development and its implications for human disease.
about
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor proteinHoloprosencephaly and holoprosencephaly-like phenotype and GAS1 DNA sequence changes: Report of four Brazilian patientsA sonic hedgehog missense mutation associated with holoprosencephaly causes defective binding to GAS1Global gene profiling of spontaneous hepatocellular carcinoma in B6C3F1 mice: similarities in the molecular landscape with human liver cancerGrowth Arrest Specific-1 (GAS1) Is a C/EBP Target Gene That Functions in Ovulation and Corpus Luteum Formation in MiceTranscriptome microRNA profiling of bovine mammary epithelial cells challenged with Escherichia coli or Staphylococcus aureus bacteria reveals pathogen directed microRNA expression profiles.Genome-wide detection of allele specific copy number variation associated with insulin resistance in African Americans from the HyperGEN study.Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function.Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks.Solution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1.Overweight in mice and enhanced adipogenesis in vitro are associated with lack of the hedgehog coreceptor boc.Activation of two distinct Sox9-EGFP-expressing intestinal stem cell populations during crypt regeneration after irradiation.LncRNA-Hh Strengthen Cancer Stem Cells Generation in Twist-Positive Breast Cancer via Activation of Hedgehog Signaling PathwayMissense substitutions in the GAS1 protein present in holoprosencephaly patients reduce the affinity for its ligand, SHH.The ups and downs of holoprosencephaly: dorsal versus ventral patterning forces.Identification of GAS1 as an epirubicin resistance-related gene in human gastric cancer cells with a partially randomized small interfering RNA libraryGas1 Knockdown Increases the Neuroprotective Effect of Glial Cell-Derived Neurotrophic Factor Against Glutamate-Induced Cell Injury in Human SH-SY5Y Neuroblastoma Cells.Integrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancerGastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling.Growth arrest-specific gene 1 is downregulated and inhibits tumor growth in gastric cancer.A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor gene.Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferationGenetic interactions between the hedgehog co-receptors Gas1 and Boc regulate cell proliferation during murine palatogenesis.Gas1 interferes with AβPP trafficking by facilitating the accumulation of immature AβPP in endoplasmic reticulum-associated raft subdomainsAnnexin A1, Annexin A2, and Dyrk 1B are upregulated during GAS1-induced cell cycle arrest.FOS proliferating network construction in early colorectal cancer (CRC) based on integrative significant function cluster and inferring analysis.MicroRNA-34a is dispensable for p53 function as teratogenesis inducer.Gas1 expression in parietal cells of Bowman's capsule in experimental diabetic nephropathy.
P2860
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P2860
The role of Gas1 in embryonic development and its implications for human disease.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
The role of Gas1 in embryonic development and its implications for human disease.
@en
type
label
The role of Gas1 in embryonic development and its implications for human disease.
@en
prefLabel
The role of Gas1 in embryonic development and its implications for human disease.
@en
P356
P1433
P1476
The role of Gas1 in embryonic development and its implications for human disease.
@en
P2093
Chen-Ming Fan
David C Martinelli
P304
P356
10.4161/CC.6.21.4877
P577
2007-08-13T00:00:00Z