Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.
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Bioorthogonal chemistry: fishing for selectivity in a sea of functionalityAzidation in the Difunctionalization of OlefinsClick chemistry in peptide-based drug designAlkyne-azide "click" chemistry in designing nanocarriers for applications in biologyEnzyme immobilization: an updateConformational Remodeling of Femtomolar Inhibitor−Acetylcholinesterase Complexes in the Crystalline StateStereo- and regioselective azide/alkyne cycloadditions in carbonic anhydrase II via tethering, monitored by crystallography and mass spectrometryRapid preparation of triazolyl substituted NH-heterocyclic kinase inhibitors via one-pot Sonogashira coupling-TMS-deprotection-CuAAC sequenceHuprine derivatives as sub-nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X-ray crystallographyTriazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosisNovel Phospholipid-Protein Conjugates Allow Improved Detection of Antibodies in Patients with Autoimmune DiseasesEnzymatic Macrocyclization of 1,2,3-Triazole Peptide MimeticsQ28828613Effects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function.Regioselective intramolecular dipolar cycloaddition of azides and unsymmetrical alkynesLibrary of 1,4-disubstituted 1,2,3-triazole analogs of oxazolidinone RNA-binding agents.Peptide and glycopeptide dendrimers and analogous dendrimeric structures and their biomedical applications.Expedient Synthesis of SMAMPs via Click Chemistry.Targeting tuberculosis through a small focused library of 1,2,3-triazoles.Synthesis and preliminary evaluation steroidal antiestrogen-geldanamycin conjugates.Synthesis of a DOTA--biotin conjugate for radionuclide chelation via Cu-free click chemistry.Pyridine-based lanthanide complexes combining MRI and NIR luminescence activities.Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors.Triazole-containing monophosphate mRNA cap analogs as effective translation inhibitorsOne-pot three-step synthesis of 1,2,3-triazoles by copper-catalyzed cycloaddition of azides with alkynes formed by a Sonogashira cross-coupling and desilylation.The impact of click chemistry in medicinal chemistry.1,2,4-trisubstituted cyclopentanes as platforms for diversity.Radioiodinated O(6)-Benzylguanine derivatives containing an azido function.Optimization of the anti-cancer activity of phosphatidylinositol-3 kinase pathway inhibitor PITENIN-1: switching a thiourea with 1,2,3-triazoleCopper-catalyzed azide-alkyne cycloaddition (CuAAC) and beyond: new reactivity of copper(I) acetylides.Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands.Click chemistry patents and their impact on drug discovery and chemical biology.Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors.Synthesis and Evaluation of a Rationally Designed Click-Based Library for G-Quadruplex Selective DNA Photocleavage.Top-down mass spectrometry of hybrid materials with hydrophobic peptide and hydrophilic or hydrophobic polymer blocks.Synthesis of 1,2,3-triazol-1-yl-methaneboronic acids via click chemistry: an easy access to a new potential scaffold for protease inhibitors.Synthesis of alpha-tetrasubstituted triazoles by copper-catalyzed silyl deprotection/azide cycloaddition.1,2,3-Triazoles as Amide Bioisosteres: Discovery of a New Class of Potent HIV-1 Vif Antagonists.Synthesis of Novel Saccharin Derivatives.Synthesis of Farnesol Analogues Containing Triazoles in Place of Isoprenes through 'Click Chemistry'
P2860
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P2860
Click chemistry reactions in medicinal chemistry: applications of the 1,3-dipolar cycloaddition between azides and alkynes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Click chemistry reactions in m ...... on between azides and alkynes.
@en
type
label
Click chemistry reactions in m ...... on between azides and alkynes.
@en
prefLabel
Click chemistry reactions in m ...... on between azides and alkynes.
@en
P2093
P356
P1476
Click chemistry reactions in m ...... ion between azides and alkynes
@en
P2093
Gian Cesare Tron
Giovanni Sorba
Pier Luigi Canonico
Tracey Pirali
P304
P356
10.1002/MED.20107
P577
2008-03-01T00:00:00Z