The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
about
MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cellsBoth hMutSα and hMutSß DNA mismatch repair complexes participate in 5-fluorouracil cytotoxicity.Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.Identification of reproducible drug-resistance-related dysregulated genes in small-scale cancer cell line experiments.Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.CCT244747 is a novel potent and selective CHK1 inhibitor with oral efficacy alone and in combination with genotoxic anticancer drugs.DNA mismatch repair and the DNA damage response.Participation of DNA repair in the response to 5-fluorouracil.Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress.Methoxyamine Enhances 5-Fluorouracil-Induced Radiosensitization in Colon Cancer Cell Line HT29.Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy.P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance.DNA mismatch repair proficiency executing 5-fluorouracil cytotoxicity in colorectal cancer cells.Abrogation of microsatellite-instable tumors using a highly selective suicide gene/prodrug combination.In vitro and in vivo antiproliferative effect of a combination of ultraviolet-A and alkoxy furocoumarins isolated from Umbelliferae medicinal plants, in melanoma cells.Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke.Anti-tumor effects of various furocoumarins isolated from the roots, seeds and fruits of Angelica and Cnidium species under ultraviolet A irradiation.
P2860
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P2860
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
@en
type
label
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
@en
prefLabel
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
@en
P2093
P2860
P356
P1476
The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.
@en
P2093
Ken-Ichi Yoshioka
Peggy Hsieh
Vincenzo Salerno
P2860
P304
P356
10.1002/JCB.21824
P577
2008-09-01T00:00:00Z