Participation of DNA repair in the response to 5-fluorouracil.
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The clinical value of aberrant epigenetic changes of DNA damage repair genes in human cancerInter-individual variation in DNA repair capacity: a need for multi-pathway functional assays to promote translational DNA repair researchIdentification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1Functional DNA repair signature of cancer cell lines exposed to a set of cytotoxic anticancer drugs using a multiplexed enzymatic repair assay on biochipNew insights into the RNA-based mechanism of action of the anticancer drug 5'-fluorouracil in eukaryotic cellsNew frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targetsPolymerase incorporation and miscoding properties of 5-chlorouracil.MicroRNA binding site polymorphisms as biomarkers in cancer management and research.Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.5-Fluorouracil derivatives: a patent review.SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stressEffect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.Dynamics of uracil and 5-fluorouracil in DNA.Fourier transform infrared microspectroscopy monitoring of 5-fluorouracil-induced apoptosis in SW620 colon cancer cells.Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.Enhancement of 5-fluorouracil-induced in vitro and in vivo radiosensitization with MEK inhibition.UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer5-Fluorouracil sensitizes colorectal tumor cells towards double stranded DNA breaks by interfering with homologous recombination repair.Identification of reproducible drug-resistance-related dysregulated genes in small-scale cancer cell line experiments.DNA Damage Response Assessments in Human Tumor Samples Provide Functional Biomarkers of Radiosensitivity.Smad4 loss promotes lung cancer formation but increases sensitivity to DNA topoisomerase inhibitors.Identification of DNA repair pathways that affect the survival of ovarian cancer cells treated with a poly(ADP-ribose) polymerase inhibitor in a novel drug combination.Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous RecombinationDetection of uracil within DNA using a sensitive labeling method for in vitro and cellular applications.C. elegans lifespan extension by osmotic stress requires FUdR, base excision repair, FOXO, and sirtuins.5-Fluorouracil-induced RNA stress engages a TRAIL-DISC-dependent apoptosis axis facilitated by p53.5-Fluorouracil mediated anti-cancer activity in colon cancer cells is through the induction of Adenomatous Polyposis Coli: Implication of the long-patch base excision repair pathway.Cadmium modifies the cell cycle and apoptotic profiles of human breast cancer cells treated with 5-fluorouracilImpairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.CITED2 in breast carcinoma as a potent prognostic predictor associated with proliferation, migration and chemoresistance.Nicotinamide N-methyltransferase enhances resistance to 5-fluorouracil in colorectal cancer cells through inhibition of the ASK1-p38 MAPK pathway.Bcl2 overexpression rescues the hematopoietic stem cell defects in Ku70-deficient mice by restoration of quiescenceInhibition of uracil DNA glycosylase sensitizes cancer cells to 5-fluorodeoxyuridine through replication fork collapse-induced DNA damage.RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas.Base pairing configuration and stability of an oligonucleotide duplex containing a 5-chlorouracil-adenine base pair.pH-Dependent configurations of a 5-chlorouracil-guanine base pair.Hyperthermic intraperitoneal chemotherapy with mitomycin C and 5-fluorouracil in patients at high risk of peritoneal metastasis from colorectal cancer: A preliminary clinical studyEmerging biomarkers in breast cancer care.TAS-102, a novel antitumor agent: a review of the mechanism of action.
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Participation of DNA repair in the response to 5-fluorouracil.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Participation of DNA repair in the response to 5-fluorouracil.
@en
Participation of DNA repair in the response to 5-fluorouracil.
@nl
type
label
Participation of DNA repair in the response to 5-fluorouracil.
@en
Participation of DNA repair in the response to 5-fluorouracil.
@nl
prefLabel
Participation of DNA repair in the response to 5-fluorouracil.
@en
Participation of DNA repair in the response to 5-fluorouracil.
@nl
P2860
P1476
Participation of DNA repair in the response to 5-fluorouracil.
@en
P2093
P2860
P2888
P304
P356
10.1007/S00018-008-8557-5
P577
2009-03-01T00:00:00Z