Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response.

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Q49200196-537F324E-5D20-4978-B0AA-F13930757D11

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Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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2015 nî lūn-bûn

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2015年論文

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2015年論文

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Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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P1476

Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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P2093

Dirk Homann

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P2860

Beta cells are responsible for CXCR3-mediated T-cell infiltration in insulitis

Population dynamics of islet-infiltrating cells in autoimmune diabetes.

Expression and regulation of chemokines in murine and human type 1 diabetes.

Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients.

Functional redundancy of CXCR3/CXCL10 signaling in the recruitment of diabetogenic cytotoxic T lymphocytes to pancreatic islets in a virally induced autoimmune diabetes model

Trials in type 1 diabetes: Antigen-specific therapies.

CXCR3, CXCL10 and type 1 diabetes.

Among CXCR3 chemokines, IFN-gamma-inducible protein of 10 kDa (CXC chemokine ligand (CXCL) 10) but not monokine induced by IFN-gamma (CXCL9) imprints a pattern for the subsequent development of autoimmune disease.

Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus-induced mouse model.

CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

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3990-3992

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scholarly article

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10.2337/DBI15-0019

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English

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Dirk Homann

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2015-12-01T00:00:00Z

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284709409

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P698

26604174

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type-1 diabetes

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4876762

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Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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P2860

P2860

Back From the Brink: The Uses of Targeting the CXCL10:CXCR3 Axis in Type 1 Diabetes

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type

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P1433

P1476

P2093

P2860

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P356

P407

P433

P478

P50

P577

P5875

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

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P698

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