Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice.
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Conceptualizing neurodevelopmental disorders through a mechanistic understanding of fragile X syndrome and Williams syndromeShotgun proteomics in neuroscienceDysregulation and restoration of translational homeostasis in fragile X syndromeApproaches for targeted proteomics and its potential applications in neuroscienceAltered Neuronal and Circuit Excitability in Fragile X Syndrome.Astrocytes conspire with neurons during progression of neurological diseaseRecent advances in quantitative neuroproteomicsMetabolic turnover of synaptic proteins: kinetics, interdependencies and implications for synaptic maintenanceIdentification and characterisation of Simiate, a novel protein linked to the fragile X syndromeCYFIP1 coordinates mRNA translation and cytoskeleton remodeling to ensure proper dendritic spine formationAntipurinergic therapy corrects the autism-like features in the Fragile X (Fmr1 knockout) mouse model.15N-labeled brain enables quantification of proteome and phosphoproteome in cultured primary neurons.Fragile X mental retardation protein is required for programmed cell death and clearance of developmentally-transient peptidergic neurons.FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channelsDual-pressure linear ion trap mass spectrometer improving the analysis of complex protein mixtures.Activity-dependent regulation of release probability at excitatory hippocampal synapses: a crucial role of fragile X mental retardation protein in neurotransmissionQuantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional actionQuantitative proteomics in laser capture microdissected sleep nuclei from rat brain.Regulation of protein levels in subcellular domains through mRNA transport and localized translation.Neuropeptide Release is Impaired in a Mouse Model of Fragile X Mental Retardation Syndrome.Meeting at the crossroads: common mechanisms in Fragile X and Down syndromeShort- and long-term memory are modulated by multiple isoforms of the fragile X mental retardation proteinA genetic engineering solution to the "arginine conversion problem" in stable isotope labeling by amino acids in cell culture (SILAC).Quantitative proteomics of Spodoptera frugiperda cells during growth and baculovirus infection.Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia.Stable isotope labeling by amino acids in cultured primary neuronsRescue of fragile X syndrome phenotypes in Fmr1 KO mice by a BKCa channel opener molecule.Genetic controls balancing excitatory and inhibitory synaptogenesis in neurodevelopmental disorder models.Study of neurotrophin-3 signaling in primary cultured neurons using multiplex stable isotope labeling with amino acids in cell culture.Regulation of molecular pathways in the Fragile X Syndrome: insights into Autism Spectrum DisordersVisual sensorial impairments in neurodevelopmental disorders: evidence for a retinal phenotype in Fragile X SyndromeGlycogen synthase kinase-3: a promising therapeutic target for fragile x syndromeImpaired inhibitory control of cortical synchronization in fragile X syndrome.Fragile X syndrome: the GABAergic system and circuit dysfunction.Proteomics of the Synapse--A Quantitative Approach to Neuronal Plasticity.Fmr1 deficiency promotes age-dependent alterations in the cortical synaptic proteome.A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation.Promiscuous or discriminating: Has the favored mRNA target of Fragile X Mental Retardation Protein been overlooked?The fragile X mental retardation protein in circadian rhythmicity and memory consolidation.Identification of functional marker proteins in the mammalian growth cone.
P2860
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P2860
Quantitative proteomic analysis of primary neurons reveals diverse changes in synaptic protein content in fmr1 knockout mice.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Quantitative proteomic analysi ...... content in fmr1 knockout mice.
@en
type
label
Quantitative proteomic analysi ...... content in fmr1 knockout mice.
@en
prefLabel
Quantitative proteomic analysi ...... content in fmr1 knockout mice.
@en
P2093
P2860
P356
P1476
Quantitative proteomic analysi ...... content in fmr1 knockout mice.
@en
P2093
John R Yates
Lujian Liao
Peter Vanderklish
Sung Kyu Park
P2860
P304
15281-15286
P356
10.1073/PNAS.0804678105
P407
P577
2008-09-30T00:00:00Z