The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity. - Wikidata - awgldk - TriplyDB

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.

The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.

http://www.wikidata.org/entity/Q36931760

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TRPM2 links oxidative stress to NLRP3 inflammasome activation Interleukin-1 in the pathogenesis and treatment of inflammatory diseases The inflammasome: in memory of Dr. Jurg Tschopp Caspase-1 inhibitors from an extremophilic fungus that target specific leukemia cell lines Metabolic Inflammation-Differential Modulation by Dietary Constituents Adipose tissue macrophages: going off track during obesity The Macrophage Switch in Obesity Development Is immunity a mechanism contributing to statin-induced diabetes?Treating rheumatological diseases and co-morbidities with interleukin-1 blocking therapies Kupffer cells in the liver The immune system's involvement in obesity-driven type 2 diabetes Inflammasomes: mechanism of action, role in disease, and therapeutics The immune system as a sensor of the metabolic state Inflammasome in intestinal inflammation and cancer Fat in flames: influence of cytokines and pattern recognition receptors on adipocyte lipolysis Regulation of stem cell differentiation in adipose tissue by chronic inflammation Implication of inflammatory signaling pathways in obesity-induced insulin resistance Dysfunctional adipose tissue and low-grade inflammation in the management of the metabolic syndrome: current practices and future advances Molecular Pathogenesis of NASH Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation Mitochondria: diversity in the regulation of the NLRP3 inflammasome.Inflammasomes and metabolic disorders: old genes in modern diseases NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases.Deficiency of oncostatin M receptor β (OSMRβ) exacerbates high-fat diet-induced obesity and related metabolic disorders in mice.IL1β down-regulation of sex hormone-binding globulin production by decreasing HNF-4α via MEK-1/2 and JNK MAPK pathways.Mechanisms of inflammatory responses in obese adipose tissue.Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes.Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling.Endothelial NLRP3 inflammasome activation and arterial neointima formation associated with acid sphingomyelinase during hypercholesterolemia Inflammasomes: molecular regulation and implications for metabolic and cognitive diseases Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes.NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism.NLRP3 inflammasome activation and interleukin-1β release in macrophages require calcium but are independent of calcium-activated NADPH oxidases Adipose tissue remodeling as homeostatic inflammation.Beyond canonical inflammasomes: emerging pathways in IL-1-mediated autoinflammatory disease ATP release from dying autophagic cells and their phagocytosis are crucial for inflammasome activation in macrophages A decade of progress in adipose tissue macrophage biology.Microbiota and diabetes: an evolving relationship.Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation.

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The inflammasome-mediated caspase-1 activation controls adipocyte differentiation and insulin sensitivity.

http://www.wikidata.org/entity/Q36931760

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The inflammasome-mediated casp ...... ation and insulin sensitivity.

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The inflammasome-mediated casp ...... ation and insulin sensitivity.

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The inflammasome-mediated casp ...... ation and insulin sensitivity.

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J.CMET.2010.11.011

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Cell Metabolism

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The inflammasome-mediated casp ...... ation and insulin sensitivity.

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Anneke Hijmans

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Bart-Jan Kullberg

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Berry van Tits

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Cees J Tack

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Giamilla Fantuzzi

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Janna A van Diepen

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Jos W M van der Meer

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Leo A B Joosten

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Michael Müller

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Mihai G Netea

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P2860

Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes

Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

Inflammation and metabolic disorders

Obesity is associated with macrophage accumulation in adipose tissue

Characterization of a human preadipocyte cell strain with high capacity for adipose differentiation

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Interleukin-1-receptor antagonist in type 2 diabetes mellitus

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593-605

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10.1016/J.CMET.2010.11.011

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6

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12

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Martin Wabitsch

Nico van Rooijen

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2010-12-01T00:00:00Z

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49637250

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21109192

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