Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways - Wikidata - awgldk - TriplyDB

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways

http://www.wikidata.org/entity/Q36932188

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Cell-surface receptors transactivation mediated by g protein-coupled receptors Phosphatidylserine exposure is required for ADAM17 sheddase function Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.EGF receptor ligands: recent advances PI3kα and STAT1 Interplay Regulates Human Mesenchymal Stem Cell Immune Polarization Preferred SH3 domain partners of ADAM metalloproteases include shared and ADAM-specific SH3 interactions.Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.A1 adenosine receptor-stimulated exocytosis in bladder umbrella cells requires phosphorylation of ADAM17 Ser-811 and EGF receptor transactivation.Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.N-terminal cleavage and release of the ectodomain of Flt1 is mediated via ADAM10 and ADAM 17 and regulated by VEGFR2 and the Flt1 intracellular domain High-throughput protease activity cytometry reveals dose-dependent heterogeneity in PMA-mediated ADAM17 activation.Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance Growth factor and co-receptor release by structural regulation of substrate metalloprotease accessibility.The HER2 Signaling Network in Breast Cancer--Like a Spider in its Web.Fine Tuning Cell Migration by a Disintegrin and Metalloproteinases.Polo-like kinase 2, a novel ADAM17 signaling component, regulates tumor necrosis factor α ectodomain shedding.Recent Advances in ADAM17 Research: A Promising Target for Cancer and Inflammation.Functional Genomics Approach Identifies Novel Signaling Regulators of TGFα Ectodomain Shedding.Multiple non-catalytic ADAMs are novel integrin α4 ligands.Hypercapnia attenuates ventilator-induced lung injury via a disintegrin and metalloprotease-17.Simultaneous Detection of Metalloprotease Activities in Complex Biological Samples Using the PrAMA (Proteolytic Activity Matrix Assay) Method.Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway.Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer.Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.

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P2860

Regulated ADAM17-dependent EGF family ligand release by substrate-selecting signaling pathways

http://www.wikidata.org/entity/Q36932188

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

@zh-hk

2013年論文

@zh-mo

2013年論文

@zh-tw

2013年论文

@wuu

2013年论文

@zh

2013年论文

@zh-cn

name

Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways

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type

label

Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways

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prefLabel

Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways

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PNAS.1307478110

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Regulated ADAM17-dependent EGF ...... e-selecting signaling pathways

@en

P2093

Andreas Herrlich

http://www.w3.org/2001/XMLSchema#string

David E Root

http://www.w3.org/2001/XMLSchema#string

Efrain Cermeno

http://www.w3.org/2001/XMLSchema#string

George W Bell

http://www.w3.org/2001/XMLSchema#string

Michelle Dang

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Miles A Miller

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Monika Hartmann

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Nicole Armbruster

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P2860

GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.

Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitors

Protein kinase C delta and eta isoenzymes control the shedding of the interleukin 6 receptor alpha in myeloma cells

PKCα and PKCδ regulate ADAM17-mediated ectodomain shedding of heparin binding-EGF through separate pathways.

Interleukin-1 stimulates ADAM17 through a mechanism independent of its cytoplasmic domain or phosphorylation at threonine 735

ADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.

Discovery of novel inhibitors of a disintegrin and metalloprotease 17 (ADAM17) using glycosylated and non-glycosylated substrates.

TGF-alpha mediates genetic susceptibility to chronic kidney disease.

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9776-9781

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scholarly article

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10.1073/PNAS.1307478110

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24

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110

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Douglas A Lauffenburger

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2013-05-29T00:00:00Z

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236968485

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23720309

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3683718

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