Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein
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Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolismModulation of statin-activated shedding of Alzheimer APP ectodomain by ROCKUnfolded Protein Response and Macroautophagy in Alzheimer's, Parkinson's and Prion DiseasesAPP processing in Alzheimer's diseaseMunc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processingSerotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretionNeuroprotective secreted amyloid precursor protein acts by disrupting amyloid precursor protein dimers.Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathwayCalcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures.The role of cerebral amyloid beta accumulation in common forms of Alzheimer disease.Modulation of amyloid beta protein precursor processing as a means of retarding progression of Alzheimer's diseaseSecretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity.Amyloid precursor protein processing is stimulated by metabotropic glutamate receptors.Secretases as therapeutic targets for the treatment of Alzheimer's disease.New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer's diseaseEffects of fatty acid unsaturation numbers on membrane fluidity and α-secretase-dependent amyloid precursor protein processing.Apomorphine and Alzheimer Aβ: roles for regulated α cleavage, autophagy, and antioxidation?Targets for AD treatment: conflicting messages from γ-secretase inhibitorsEffect of protein kinase A inhibitors on the production of Abeta40 and Abeta42 by human cells expressing normal and Alzheimer's disease-linked mutated betaAPP and presenilin 1.Calcium regulates processing of the Alzheimer amyloid protein precursor in a protein kinase C-independent manner.Characterization of alternative routes for processing of the Alzheimer beta/A4-amyloid precursor protein. Differential effects of phorbol esters and chloroquine.The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment.Cognitive changes and modified processing of amyloid precursor protein in the cortical and hippocampal system after cholinergic synapse loss and muscarinic receptor activationAstrocytes regulate α-secretase-cleaved soluble amyloid precursor protein secretion in neuronal cells: Involvement of group IIA secretory phospholipase A2Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts.Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degenerationAltered processing of Alzheimer amyloid precursor protein in response to neuronal degenerationTherapeutic targeting of the endoplasmic reticulum in Alzheimer's disease.Study of the synthesis and secretion of normal and artificial mutants of murine amyloid precursor protein (APP): cleavage of APP occurs in a late compartment of the default secretion pathway.Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiopPost-transcriptional contribution of a cAMP-dependent pathway to the formation of alpha- and beta/gamma-secretases-derived products of beta APP maturation in human cells expressing wild-type and Swedish mutated beta APP.Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide.Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis.Proteolytic processing of the Alzheimer disease-associated presenilin-1 generates an in vivo substrate for protein kinase C.Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursorPotential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.Metabolism of Alzheimer beta-amyloid precursor protein: regulation by protein kinase A in intact cells and in a cell-free system.Identification and biology of α-secretase.High-level expression and in vitro mutagenesis of a fibrillogenic 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein.Differential effects of a Rab6 mutant on secretory versus amyloidogenic processing of Alzheimer's beta-amyloid precursor protein.
P2860
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P2860
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Protein phosphorylation regula ...... a/A4 amyloid precursor protein
@en
type
label
Protein phosphorylation regula ...... a/A4 amyloid precursor protein
@en
prefLabel
Protein phosphorylation regula ...... a/A4 amyloid precursor protein
@en
P2093
P2860
P356
P1476
Protein phosphorylation regula ...... a/A4 amyloid precursor protein
@en
P2093
G L Caporaso
J D Buxbaum
T V Ramabhadran
P2860
P304
P356
10.1073/PNAS.89.7.3055
P407
P577
1992-04-01T00:00:00Z