Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
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Recent advances in understanding leptin signaling and leptin resistanceLeptin signalling, obesity and prostate cancer: molecular and clinical perspective on the old dilemmaRole of leptin and its receptors in the pathogenesis of thyroid cancerLeptin signaling and leptin resistanceLeptin enhances the potency of circulating angiogenic cells via src kinase and integrin (alpha)vbeta5: implications for angiogenesis in human obesityLeptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFkappaB/HIF-1alpha activationGlucose enhances leptin signaling through modulation of AMPK activity.The unique cysteine knot regulates the pleotropic hormone leptin.Synergistic interaction between leptin and cholecystokinin in the rat nodose ganglia is mediated by PI3K and STAT3 signaling pathways: implications for leptin as a regulator of short term satiety.Leptin modulates the intrinsic excitability of AgRP/NPY neurons in the arcuate nucleus of the hypothalamus.Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathwayIn vivo and in vitro evidence that chronic activation of the hexosamine biosynthetic pathway interferes with leptin-dependent STAT3 phosphorylation.Shp2 controls female body weight and energy balance by integrating leptin and estrogen signals.The role of GluN2A and GluN2B NMDA receptor subunits in AgRP and POMC neurons on body weight and glucose homeostasis.Amylin and leptin activate overlapping signalling pathways in an additive manner in mouse GT1-7 hypothalamic, C₂C₁₂ muscle and AML12 liver cell lines.Central insulin and leptin-mediated autonomic control of glucose homeostasis.Adipocytokines in thyroid dysfunction.Role of leptin and leptin receptors in hematological malignancies.Polymorphisms in Lep and Lepr Genes in Infants: Correlation with Serum Leptin Values in the First 6 Months of Life.Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer.Activation of target signal transducers utilizing chimeric receptors with signaling-molecule binding motifs.Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells.SH2B1 is critical for the regulation of cardiac remodelling in response to pressure overload.Hypertriglyceridemia in female rats during pregnancy induces obesity in male offspring via altering hypothalamic leptin signaling.Fyn mediates leptin actions in the thymus of rodentsGastric vagal afferent modulation by leptin is influenced by food intake status.Neonatal Overfeeding in Female Mice Predisposes the Development of Obesity in their Male Offspring via Altered Central Leptin Signalling.Geniposide attenuates the level of Aβ1-42 via enhancing leptin signaling in cellular and APP/PS1 transgenic mice.
P2860
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P2860
Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
@en
type
label
Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
@en
prefLabel
Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
@en
P2093
P2860
P356
P1476
Leptin stimulates both JAK2-dependent and JAK2-independent signaling pathways.
@en
P2093
Liangyou Rui
P2860
P304
28066-28073
P356
10.1074/JBC.M805545200
P407
P577
2008-08-21T00:00:00Z