Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
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Location and dynamics of the immunodominant CD8 T cell response to SIVΔnef immunization and SIVmac251 vaginal challengeLive attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaquesVaccination against endogenous retrotransposable element consensus sequences does not protect rhesus macaques from SIVsmE660 infection and replicationRectal HSV-2 Infection May Increase Rectal SIV Acquisition Even in the Context of SIVΔnef VaccinationCD8 T cell response maturation defined by anentropic specificity and repertoire depth correlates with SIVΔnef-induced protectionEx vivo SIV-specific CD8 T cell responses in heterozygous animals are primarily directed against peptides presented by a single MHC haplotypeGagCM9-specific CD8+ T cells expressing limited public TCR clonotypes do not suppress SIV replication in vivoLong-term central and effector SHIV-specific memory T cell responses elicited after a single immunization with a novel lentivector DNA vaccineADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challengeRecombinant Yellow Fever Vaccine Virus 17D Expressing Simian Immunodeficiency Virus SIVmac239 Gag Induces SIV-Specific CD8+ T-Cell Responses in Rhesus MacaquesDifferent Vaccine Vectors Delivering the Same Antigen Elicit CD8+ T Cell Responses with Distinct Clonotype and Epitope SpecificityPrevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccineAutologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeysRole of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV VaccineHIV-1 Tat-based vaccines: an overview and perspectives in the field of HIV/AIDS vaccine development.Animal models for HIV/AIDS researchLoss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine.Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Characterization of T-cell responses in macaques immunized with a single dose of HIV DNA vaccineProtection of macaques with diverse MHC genotypes against a heterologous SIV by vaccination with a deglycosylated live-attenuated SIV.Multi-low-dose mucosal simian immunodeficiency virus SIVmac239 challenge of cynomolgus macaques immunized with "hyperattenuated" SIV constructs.TRIM5 suppresses cross-species transmission of a primate immunodeficiency virus and selects for emergence of resistant variants in the new speciesExtralymphoid CD8+ T cells resident in tissue from simian immunodeficiency virus SIVmac239{Delta}nef-vaccinated macaques suppress SIVmac239 replication ex vivo.Dendritic cell targeted HIV gag protein vaccine provides help to a DNA vaccine including mobilization of protective CD8+ T cells.New directions for HIV vaccine development from animal models.T-cell correlates of vaccine efficacy after a heterologous simian immunodeficiency virus challenge.Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infectionRational antibody-based HIV-1 vaccine design: current approaches and future directionsIs an HIV vaccine possible?Early potent protection against heterologous SIVsmE660 challenge following live attenuated SIV vaccination in Mauritian cynomolgus macaques.The influence of delivery vectors on HIV vaccine efficacyMacaques vaccinated with simian immunodeficiency virus SIVmac239Delta nef delay acquisition and control replication after repeated low-dose heterologous SIV challenge.Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry.Host factors determine differential disease progression after infection with nef-deleted simian immunodeficiency virusDivergence, not diversity of an attenuated equine lentivirus vaccine strain correlates with protection from diseaseMacaque long-term nonprogressors resist superinfection with multiple CD8+ T cell escape variants of simian immunodeficiency virus.Vaccination with live attenuated simian immunodeficiency virus causes dynamic changes in intestinal CD4+CCR5+ T cells.The immune response during acute HIV-1 infection: clues for vaccine development.Simian immunodeficiency virus SIVmac239Deltanef vaccination elicits different Tat28-35SL8-specific CD8+ T-cell clonotypes compared to a DNA prime/adenovirus type 5 boost regimen in rhesus macaques.
P2860
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P2860
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
@en
type
label
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
@en
prefLabel
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
@en
P2093
P2860
P50
P356
P1476
Macaques vaccinated with live-attenuated SIV control replication of heterologous virus.
@en
P2093
Adrian B McDermott
Caitlin MacNair
Dan P Leaman
Dennis R Burton
Emma Gostick
Enrique J León
Eva G Rakasz
Jessica R Furlott
Kim L Weisgrau
Masahiko Kaizu
P2860
P304
P356
10.1084/JEM.20081524
P407
P577
2008-10-06T00:00:00Z