Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Item
http://www.wikidata.org/entity/Q36947793
Murine models of acute leukemia: important tools in current pediatric leukemia research.Haploinsufficiency of the c-myc transcriptional repressor FIR, as a dominant negative-alternative splicing model, promoted p53-dependent T-cell acute lymphoblastic leukemia progression by activating Notch1.Impact of PTEN abnormalities on outcome in pediatric patients with T-cell acute lymphoblastic leukemia treated on the MRC UKALL2003 trialEpigenetic instability at imprinting control regions in a Kras(G12D)-induced T-cell neoplasm.Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.Dnmt3a haploinsufficiency cooperates with oncogenic Kras to promote an early-onset T-cell acute lymphoblastic leukemia.Ras/Raf/MEK/ERK Pathway Activation in Childhood Acute Lymphoblastic Leukemia and Its Therapeutic TargetingPleiotropic roles of Notch signaling in normal, malignant, and developmental hematopoiesis in the human.Clonal evolution enhances leukemia-propagating cell frequency in T cell acute lymphoblastic leukemia through Akt/mTORC1 pathway activationEpigenetic response of imprinted domains during carcinogenesis.Aberrant Signaling Pathways in T-Cell Acute Lymphoblastic Leukemia.Mice expressing KrasG12D in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia.Wild-type KRAS inhibits oncogenic KRAS-induced T-ALL in mice.Differential Co-expression and Regulatory Network Analysis Uncover the Relapse Factor and Mechanism of T Cell Acute Leukemia.Therapeutic Targeting of mTOR in T-Cell Acute Lymphoblastic Leukemia: An Update
P2860

Notch1 gene mutations target KRAS G12D-expressing CD8+ cells and contribute to their leukemogenic transformation.

Item
http://www.wikidata.org/entity/Q36947793
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Notch1 gene mutations target K ...... r leukemogenic transformation.
@en
type
label
Notch1 gene mutations target K ...... r leukemogenic transformation.
@en
prefLabel
Notch1 gene mutations target K ...... r leukemogenic transformation.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932
P356
P1433
P1476
Notch1 gene mutations target K ...... r leukemogenic transformation.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P577
P698
P932