Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
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Forward genetic approaches for elucidation of novel regulators of Lyme arthritis severityNormal human B lymphocytes and mononuclear cells respond to the mitogenic and cytokine-stimulatory activities of Borrelia burgdorferi and its lipoprotein OspA.Borrelia burgdorferi gene expression in vivo and spirochete pathogenicity.Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cellsRelative contributions of innate and acquired host responses to bacterial control and arthritis development in Lyme diseaseBorrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory propertiesDistinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice.Lymphoadenopathy during lyme borreliosis is caused by spirochete migration-induced specific B cell activationAnti-neural antibody reactivity in patients with a history of Lyme borreliosis and persistent symptoms.Dual role of interleukin-10 in murine Lyme disease: regulation of arthritis severity and host defenseMurine model for lymphocytic tropism by Borrelia burgdorferiComparative molecular analyses of Borrelia burgdorferi sensu stricto strains B31 and N40D10/E9 and determination of their pathogenicity.Outer surface lipoproteins of Borrelia burgdorferi stimulate nitric oxide production by the cytokine-inducible pathwayBiological activities of native and recombinant Borrelia burgdorferi outer surface protein A: dependence on lipid modificationMurine Lyme arthritis development mediated by p38 mitogen-activated protein kinase activity.Fetal outcome in murine Lyme disease.Nitric oxide production during murine Lyme disease: lack of involvement in host resistance or pathology.Involvement of CD4+ T lymphocytes in induction of severe destructive Lyme arthritis in inbred LSH hamstersCD8+ T cells are activated during the early Th1 and Th2 immune responses in a murine Lyme disease model.Lyme borreliosis in transgenic mice tolerant to Borrelia burgdorferi OspA or B.Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissuesStudies on early events of Borrelia burgdorferi-induced cytokine production in immunodeficient SCID mice by using a tissue chamber model for acute inflammationT helper phenotype and genetic susceptibility in experimental Lyme diseaseMyD88 negatively controls hypergammaglobulinemia with autoantibody production during bacterial infection.Persistence of Borrelia burgdorferi following antibiotic treatment in miceGene expression profiling provides insights into the pathways involved in inflammatory arthritis development: murine model of Lyme disease.Effect of anti-interleukin 12 treatment on murine lyme borreliosis.MyD88- and TRIF-independent induction of type I interferon drives naive B cell accumulation but not loss of lymph node architecture in Lyme disease.Arthritis severity and spirochete burden are determined by serotype in the Borrelia turicatae-mouse model of Lyme disease.Effects of Ixodes scapularis and Borrelia burgdorferi on modulation of the host immune response: induction of a TH2 cytokine response in Lyme disease-susceptible (C3H/HeJ) mice but not in disease-resistant (BALB/c) mice.Lipopeptides of Borrelia burgdorferi outer surface proteins induce Th1 phenotype development in alphabeta T-cell receptor transgenic mice.A role for T cells in the pathogenesis of treatment-resistant Lyme arthritisPresence of Arp specifically contributes to joint tissue edema associated with early-onset Lyme arthritis.Autoantigen, innate immunity, and T cells cooperate to break B cell tolerance during bacterial infection.Interleukin-6 promotes anti-OspA borreliacidal antibody production in vitro.
P2860
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P2860
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
1992年论文
@zh
1992年论文
@zh-cn
name
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
@en
type
label
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
@en
prefLabel
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
@en
P2093
P2860
P1476
Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice.
@en
P2093
E Eichwald
M Griffiths
R Schoenfeld
P2860
P304
P407
P577
1992-08-01T00:00:00Z