Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography

about

Effects of HM30181, a P-glycoprotein inhibitor, on the pharmacokinetics and pharmacodynamics of loperamide in healthy volunteers.Effects of Muscone on the Expression of P-gp, MMP-9 on Blood-Brain Barrier Model In Vitro.Enhanced oral bioavailability of paclitaxel by solid dispersion granulation.

P2860

Q34571054-74A63CF3-4849-45D9-A48E-0C8106E8A997 Q48176807-4FBCB258-8613-45EF-962E-6B9941D99680 Q53229493-928BDB52-5F65-4B0E-8E7D-1CAAEE0BDD00

P2860

Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography

Item

http://www.wikidata.org/entity/Q36949407

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Interaction of HM30181 with P- ...... h positron emission tomography

@en

type

Item

label

Interaction of HM30181 with P- ...... h positron emission tomography

@en

prefLabel

Interaction of HM30181 with P- ...... h positron emission tomography

@en

P1476

Interaction of HM30181 with P- ...... h positron emission tomography

@en

P2093

Florian Bauer

http://www.w3.org/2001/XMLSchema#string

Johann Stanek

http://www.w3.org/2001/XMLSchema#string

Markus Müller

http://www.w3.org/2001/XMLSchema#string

Michael Sauberer

http://www.w3.org/2001/XMLSchema#string

Peter Chiba

http://www.w3.org/2001/XMLSchema#string

Thomas Erker

http://www.w3.org/2001/XMLSchema#string

Thomas Wanek

http://www.w3.org/2001/XMLSchema#string

Zahida Parveen

http://www.w3.org/2001/XMLSchema#string

P2860

Development of a P-glycoprotein knockout model in rodents to define species differences in its functional effect at the blood-brain barrier

P-glycoprotein function at the blood-brain barrier in humans can be quantified with the substrate radiotracer 11C-N-desmethyl-loperamide.

Pgp-mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier: a comparison with rat data

Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development.

Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: clinical significance of in vitro and in vivo findings.

Breast cancer resistance protein and P-glycoprotein in brain cancer: two gatekeepers team up

The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.

Tariquidar (XR9576): a P-glycoprotein drug efflux pump inhibitor.

A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein-expressing murine breast cancer.

P304

18-27

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.EJPHAR.2012.09.013

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

1-3

http://www.w3.org/2001/XMLSchema#string

P478

696

http://www.w3.org/2001/XMLSchema#string

P50

Oliver Langer

Claudia Kuntner

Severin Mairinger

P577

2012-09-26T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

23022332

http://www.w3.org/2001/XMLSchema#string

P921

blood–brain barrier

P932

3690544

http://www.w3.org/2001/XMLSchema#string

Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography

about

P2860

P2860

Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932