Targeting the androgen receptor pathway in prostate cancer.
about
Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancerHormonal therapy and chemotherapy in hormone-naive and castration resistant prostate cancerMechanisms of resistance in castration-resistant prostate cancer (CRPC)Mediator kinase module and human tumorigenesisSteroid Receptor-Associated Immunophilins: A Gateway to Steroid SignallingOncolytic adenovirus-mediated therapy for prostate cancerTurning off AKT: PHLPP as a drug targetCentral role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancerAck1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancerEDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting ChemicalsModulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screeningPharmacologic blockade and genetic deletion of androgen receptor attenuates aortic aneurysm formation.The Concise Guide to PHARMACOLOGY 2013/14: nuclear hormone receptors.Proteomic analysis of the androgen receptor via MS-compatible purification of biotinylated protein on streptavidin resin.Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data.Coactivator MYST1 regulates nuclear factor-κB and androgen receptor functions during proliferation of prostate cancer cells.The Effects and Mechanism of YK-4-279 in Combination with Docetaxel on Prostate Cancer.Minireview: Not picking pockets: nuclear receptor alternate-site modulators (NRAMs)Partners in crime: deregulation of AR activity and androgen synthesis in prostate cancerTwo panels of steroid receptor luciferase reporter cell lines for compound profiling.IGF2 revs the steroidogenesis engine.From DNA binding to metabolic control: integration of -omics data reveals drug targets for prostate cancer.High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.Alternative inhibition of androgen receptor signaling: peptidomimetic pyrimidines as direct androgen receptor/coactivator disruptors.The impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activitymiR 488* inhibits androgen receptor expression in prostate carcinoma cellsDHT selectively reverses Smad3-mediated/TGF-beta-induced responses through transcriptional down-regulation of Smad3 in prostate epithelial cellsSensitive detection of pathway perturbations in cancersShort hairpin RNA library-based functional screening identified ribosomal protein L31 that modulates prostate cancer cell growth via p53 pathwayA screen for transcription factor targets of glycogen synthase kinase-3 highlights an inverse correlation of NFκB and androgen receptor signaling in prostate cancerSmall molecule inhibitors as probes for estrogen and androgen receptor actionGreen tea polyphenol EGCG blunts androgen receptor function in prostate cancer.Differential transformation capacity of Src family kinases during the initiation of prostate cancer.Early human prostate adenocarcinomas harbor androgen-independent cancer cellsNoninvasive measurement of androgen receptor signaling with a positron-emitting radiopharmaceutical that targets prostate-specific membrane antigenThe course of metastatic prostate cancer under treatment.Angiogenin as a molecular target for the treatment of prostate cancer.Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth.Hedgehog signaling in prostate epithelial-mesenchymal growth regulation.The hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells.
P2860
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P2860
Targeting the androgen receptor pathway in prostate cancer.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Targeting the androgen receptor pathway in prostate cancer.
@en
type
label
Targeting the androgen receptor pathway in prostate cancer.
@en
prefLabel
Targeting the androgen receptor pathway in prostate cancer.
@en
P2093
P2860
P1476
Targeting the androgen receptor pathway in prostate cancer.
@en
P2093
Charles L Sawyers
Howard I Scher
P2860
P304
P356
10.1016/J.COPH.2008.07.005
P577
2008-08-12T00:00:00Z