Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation - Wikidata - awgldk - TriplyDB

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

http://www.wikidata.org/entity/Q28301664

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Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome HECT E3 ubiquitin ligase Nedd4-1 ubiquitinates ACK and regulates epidermal growth factor (EGF)-induced degradation of EGF receptor and ACK Shepherding AKT and androgen receptor by Ack1 tyrosine kinase Regulation of androgen receptor transcriptional activity and specificity by RNF6-induced ubiquitination Non-Coding RNAs in Castration-Resistant Prostate Cancer: Regulation of Androgen Receptor Signaling and Cancer Metabolism Cross talk of tyrosine kinases with the DNA damage signaling pathways Androgen receptor activation in castration-recurrent prostate cancer: the role of Src-family and Ack1 tyrosine kinases The tumor suppressor gene, RASSF1A, is essential for protection against inflammation -induced injury Ack1: Activation and Regulation by Allostery A novel androgen receptor splice variant is up-regulated during prostate cancer progression and promotes androgen depletion-resistant growth CrkI and p130(Cas) complex regulates the migration and invasion of prostate cancer cells Development of novel ACK1/TNK2 inhibitors using a fragment-based approach PI3K-independent AKT activation in cancers: a treasure trove for novel therapeutics Ack1 tyrosine kinase activation correlates with pancreatic cancer progression Ack1-mediated androgen receptor phosphorylation modulates radiation resistance in castration-resistant prostate cancer ACK1 tyrosine kinase: targeted inhibition to block cancer cell proliferation Drosophila activated Cdc42 kinase has an anti-apoptotic function Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.The Cdc42-associated kinase ACK1 is not autoinhibited but requires Src for activation.Cancer-associated mutations activate the nonreceptor tyrosine kinase Ack1.Androgen receptor phosphorylation: biological context and functional consequences.CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases The neuroendocrine-derived peptide parathyroid hormone-related protein promotes prostate cancer cell growth by stabilizing the androgen receptor.Gene profiles between non-invasive and invasive colon cancer using laser microdissection and polypeptide analysis A role for the androgen-receptor in clinically localized and advanced prostate cancer.LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method.Minireview: Tipping the balance: ligand-independent activation of steroid receptors.Minireview: the molecular and genomic basis for prostate cancer health disparities TPL2/COT/MAP3K8 (TPL2) activation promotes androgen depletion-independent (ADI) prostate cancer growth.Identification of androgen receptor phosphorylation in the primate ovary in vivo.High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.5α-reductase type 3 expression in human benign and malignant tissues: a comparative analysis during prostate cancer progression.H2B Tyr37 phosphorylation suppresses expression of replication-dependent core histone genes ACK1 tyrosine kinase interacts with histone demethylase KDM3A to regulate the mammary tumor oncogene HOXA1 Differential requirement for Src family tyrosine kinases in the initiation, progression, and metastasis of prostate cancer Molecular pathways and targets in prostate cancer Abiraterone acetate: a promising drug for the treatment of castration-resistant prostate cancer.Minireview: Alternative activation pathways for the androgen receptor in prostate cancer.

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P2860

Activated Cdc42-associated kinase Ack1 promotes prostate cancer progression via androgen receptor tyrosine phosphorylation

http://www.wikidata.org/entity/Q28301664

description

2007 nî lūn-bûn

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2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2007 թվականի մայիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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type

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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prefLabel

Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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PNAS.0700420104

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Proceedings of the National Academy of Sciences of the United States of America

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Activated Cdc42-associated kin ...... eptor tyrosine phosphorylation

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Carol E Parker

http://www.w3.org/2001/XMLSchema#string

H Shelton Earp

http://www.w3.org/2001/XMLSchema#string

James L Mohler

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Maria R Warren

http://www.w3.org/2001/XMLSchema#string

Nupam P Mahajan

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Samarpan Majumder

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Yuanbo Liu

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P2860

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

Ack1 mediates Cdc42-dependent cell migration and signaling to p130Cas

Receptor for activated C kinase 1 (RACK1) and Src regulate the tyrosine phosphorylation and function of the androgen receptor

Cloning and mRNA expression analysis of a novel human protooncogene, c-mer

The AF1 and AF2 domains of the androgen receptor interact with distinct regions of SRC1

Sequence and structure-based prediction of eukaryotic protein phosphorylation sites

Activation of the guanine nucleotide exchange factor Dbl following ACK1-dependent tyrosine phosphorylation

Molecular determinants of resistance to antiandrogen therapy

Activated tyrosine kinase Ack1 promotes prostate tumorigenesis: role of Ack1 in polyubiquitination of tumor suppressor Wwox

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10.1073/PNAS.0700420104

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20

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104

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phosphorylation

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1895968

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