Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity.
about
Neurobehavioral abnormalities in a brain-specific NADPH-cytochrome P450 reductase knockout mouse modelThe role of small-intestinal P450 enzymes in protection against systemic exposure of orally administered benzo[a]pyreneDrug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models.Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome: role of a redox enzyme in development.NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.Role of mammary epithelial and stromal P450 enzymes in the clearance and metabolic activation of 7,12-dimethylbenz(a)anthracene in mice.An intestinal epithelium-specific cytochrome P450 (P450) reductase-knockout mouse model: direct evidence for a role of intestinal p450s in first-pass clearance of oral nifedipine.The role of renal proximal tubule P450 enzymes in chloroform-induced nephrotoxicity: utility of renal specific P450 reductase knockout mouse models.Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity.Application of a novel regulatable Cre recombinase system to define the role of liver and gut metabolism in drug oral bioavailability.Molecular population genetics of the NADPH cytochrome P450 reductase (CPR) gene in Anopheles minimus.The decrease of NAD(P)H:quinone oxidoreductase 1 activity and increase of ROS production by NADPH oxidases are early biomarkers in doxorubicin cardiotoxicity.
P2860
Q30417522-6F424D4C-1945-49E8-869A-A9E9A542697FQ34028109-7870E80A-8BAF-4302-83B1-66F306303D0CQ34513706-674D9E14-2594-450E-A5D3-4BA5AB9B7911Q35005855-ABB99AAA-BEB6-46EB-9F29-9F72546F23FAQ36497649-E1DA9B57-02DC-4DB8-B74A-5748D594350FQ36889516-6754D5F6-A559-4F94-8C4A-23CA0E79F905Q37104008-3D566305-DA6A-4AB8-A7F7-D57DD5DF1932Q37179150-EA5D1C6D-487C-4145-8D15-4B2557964ABCQ37264451-0F569E56-2E94-43D0-85B1-B433AA79CA51Q43779543-353CD0D2-A71D-407E-BEA1-6B0397E03CD9Q44144603-E8D4E4E3-D4EB-4A55-88F8-6E764A28BCD5Q46934674-504C1BFF-00D2-4FEF-9872-6FC5FDDA0677
P2860
Deletion of the NADPH-cytochrome P450 reductase gene in cardiomyocytes does not protect mice against doxorubicin-mediated acute cardiac toxicity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Deletion of the NADPH-cytochro ...... diated acute cardiac toxicity.
@en
type
label
Deletion of the NADPH-cytochro ...... diated acute cardiac toxicity.
@en
prefLabel
Deletion of the NADPH-cytochro ...... diated acute cardiac toxicity.
@en
P2093
P2860
P356
P1476
Deletion of the NADPH-cytochro ...... diated acute cardiac toxicity.
@en
P2093
Cheng Fang
E Dale Abel
Melissa Behr
Weizhu Yang
Xinxin Ding
P2860
P304
P356
10.1124/DMD.108.021881
P577
2008-05-07T00:00:00Z