Neuraminidase-1 is required for the normal assembly of elastic fibers
about
NEU1 sialidase expressed in human airway epithelia regulates epidermal growth factor receptor (EGFR) and MUC1 protein signalingRegulation of intracellular signaling by extracellular glycan remodeling.Lysosomal multienzyme complex: pros and cons of working togetherMuscle degeneration in neuraminidase 1-deficient mice results from infiltration of the muscle fibers by expanded connective tissueInhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo.Elevated expression of NEU1 sialidase in idiopathic pulmonary fibrosis provokes pulmonary collagen deposition, lymphocytosis, and fibrosis.Loss-of-function mutations in ATP6V0A2 impair vesicular trafficking, tropoelastin secretion and cell survivalImplications for the mammalian sialidases in the physiopathology of skeletal muscleExtracellular matrix components: an intricate network of possible biomarkers for lysosomal storage disorders?The NEU1-selective sialidase inhibitor, C9-butyl-amide-DANA, blocks sialidase activity and NEU1-mediated bioactivities in human lung in vitro and murine lung in vivo.
P2860
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P2860
Neuraminidase-1 is required for the normal assembly of elastic fibers
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Neuraminidase-1 is required for the normal assembly of elastic fibers
@en
type
label
Neuraminidase-1 is required for the normal assembly of elastic fibers
@en
prefLabel
Neuraminidase-1 is required for the normal assembly of elastic fibers
@en
P2093
P2860
P1476
Neuraminidase-1 is required for the normal assembly of elastic fibers
@en
P2093
Alessandra d'Azzo
Alexsander Hinek
Barry Starcher
Deepa Nadarajah
Gottipati K Rao
Patrick W Keller
P2860
P304
P356
10.1152/AJPLUNG.90346.2008
P577
2008-08-08T00:00:00Z