DNA polymerase epsilon: a polymerase of unusual size (and complexity).
about
CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol (epsilon}, and GINS in budding yeastRole of the Polymerase ϵ sub-unit DPB2 in DNA replication, cell cycle regulation and DNA damage response in Arabidopsis.Sld7, an Sld3-associated protein required for efficient chromosomal DNA replication in budding yeast.DNA polymerases at the eukaryotic fork-20 years laterDNA polymerase δ and ζ switch by sharing accessory subunits of DNA polymerase δEukaryotic genome instability in light of asymmetric DNA replicationA panoply of errors: polymerase proofreading domain mutations in cancerRibonucleotides in DNA: Origins, repair and consequencesEvolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol epsilon and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors.Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases.An iron-sulfur cluster in the polymerase domain of yeast DNA polymerase ε.The emerging genomic landscape of endometrial cancer.DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeastMechanisms of mutagenesis in vivo due to imbalanced dNTP pools.The in vitro fidelity of yeast DNA polymerase δ and polymerase ε holoenzymes during dinucleotide microsatellite DNA synthesis.Balancing eukaryotic replication asymmetry with replication fidelity.Pools and Pols: Mechanism of a mutator phenotype.Interaction pattern for the complex of B-DNA Fullerene compounds with a set of known replication proteins using docking study.Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients.Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.More than 10% of yeast genes are related to genome stability and influence cellular senescence via rDNA maintenance.Ribosomal DNA stability is supported by many 'buffer genes'-introduction to the Yeast rDNA Stability Database.Emergence of DNA polymerase ε antimutators that escape error-induced extinction in yeast.Prognostic Significance of POLE Exonuclease Domain Mutations in High-Grade Endometrioid Endometrial Cancer on Survival and Recurrence: A Subanalysis.Dividing the workload at a eukaryotic replication fork.Reconstitution of a eukaryotic replisome reveals the mechanism of asymmetric distribution of DNA polymerasesDNA polymerase epsilon and delta proofreading suppress discrete mutator and cancer phenotypes in mice.Modulation of mutagenesis in eukaryotes by DNA replication fork dynamics and quality of nucleotide pools.Regulation of human DNA polymerase delta in the cellular responses to DNA damage.Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19.Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis.DNApol-ϵ gene is indispensable for the survival and growth of Drosophila melanogaster.Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro.Inhibiting DNA Polymerases as a Therapeutic Intervention against Cancer.The human papillomavirus DNA helicase E1 binds, stimulates, and confers processivity to cellular DNA polymerase epsilon.Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.POLE somatic mutations in advanced colorectal cancer.Architecture of the Saccharomyces cerevisiae Replisome.Evidence for a role of Arabidopsis CDT1 proteins in gametophyte development and maintenance of genome integrity.
P2860
Q24622552-1595DCCA-BFF2-4F6E-9E92-782388C7F8F2Q27323204-7B24868E-E943-4D51-B162-90C2C22EA631Q27933558-B442C80A-29DC-4B1F-87E0-BC5BEED11F9BQ28255094-C07A25B3-BF82-41EF-B83E-1CB06184037DQ28263318-EF6E87A7-3BF6-4DB5-A345-31D36C042ADBQ28272691-56692D76-CD08-4E29-82F9-2CDAB0D9EC8FQ28272700-19D82BDC-1EF9-415C-9D9A-3DEBD2BC9498Q30047225-A13FD141-4708-4FA2-9313-AF2F4F6C7ED2Q30487081-AD9275A8-3369-47D5-9CD1-D814CCCE0FECQ33740206-9BB419DF-45DE-4F45-B315-B51931A6890EQ33772281-11B512EA-110F-4334-A1D7-29FA348FA173Q34026976-55E75F01-DBF8-461F-A43D-FE7909CB077AQ34311412-16CCC164-B265-43DF-A747-A1C8801A590EQ34609166-B3C32880-37EB-4CB4-B1C8-C0F38A722FA8Q35064113-C369EDB5-FC28-43DB-BD59-B81C7A86D156Q35291466-F20B4266-142B-4DC2-B2FA-C9DA4FB03D33Q35616334-2682E851-F81E-468B-BF3F-87C9D572ACE0Q35634877-99647AA7-E564-4533-BDB7-04FCF1973120Q35748591-53D4261F-01BD-44AA-8987-E18E5040E184Q35903810-016171A7-64EE-4D73-AE58-6C92EBA1D62FQ35935190-084AB3FE-B74F-4EEB-9EF1-00D266B99583Q36249659-445E0C8E-EC5C-4072-9237-62311E4DC325Q36643853-B39542E4-BC76-4EE7-AA96-FF5A414EB8DDQ36922067-E45058AD-CCA6-498A-98C5-FF7931843E3BQ37149735-1C70B5DD-4466-4FAB-93D6-6EE48CD700A8Q37289734-A59E42B8-7519-456B-AFD7-6122CB76C9C4Q37386020-0D1D78FC-5697-40AB-A9AB-7C58FA1A7B9EQ37483304-1FBB786F-93A2-49EE-BF65-01158CFB578BQ38050704-22F5BA18-23F2-4DCA-8604-BBC5D180AB1EQ38767907-0DB9A1A7-2CD1-44FF-BB15-35BB07D04D44Q40248007-D5649B44-04B7-43EB-BAB3-45E6C89236F8Q47072049-77274EDF-D98A-4D68-B743-C8A700763936Q47104826-92DB7525-34CA-42E7-94D1-02928A438FD4Q47137568-D52B4D84-F7A7-4924-9B76-6902E9492728Q47384276-9FD5ED73-B1E8-497E-A502-C5B932D740ACQ47987433-816ACCCC-FB95-47DB-806E-7380337CB372Q48125044-C39DDD89-D983-4F6B-9081-05656D283F8DQ50233460-3F7B2E97-63CB-4DDE-AE87-91DAB1FC9747Q53158412-FBFB8613-67B3-4990-9CB1-69F9D925A66B
P2860
DNA polymerase epsilon: a polymerase of unusual size (and complexity).
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
DNA polymerase epsilon: a polymerase of unusual size (and complexity).
@en
type
label
DNA polymerase epsilon: a polymerase of unusual size (and complexity).
@en
prefLabel
DNA polymerase epsilon: a polymerase of unusual size (and complexity).
@en
P2860
P1476
DNA polymerase epsilon: a polymerase of unusual size (and complexity)
@en
P2093
Thomas A Kunkel
P2860
P304
P356
10.1016/S0079-6603(08)00004-4
P577
2008-01-01T00:00:00Z