about
Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilonYeast DNA polymerase epsilon participates in leading-strand DNA replicationDNA polymerase ε and its roles in genome stabilityMismatch repair-independent increase in spontaneous mutagenesis in yeast lacking non-essential subunits of DNA polymerase ε.Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replicationCombined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancersThe high fidelity and unique error signature of human DNA polymerase epsilonDNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity.Mismatch repair balances leading and lagging strand DNA replication fidelity.Regulation of B family DNA polymerase fidelity by a conserved active site residue: characterization of M644W, M644L and M644F mutants of yeast DNA polymerase epsilon.Human Pol ε-dependent replication errors and the influence of mismatch repair on their correction.Evidence for the kinetic partitioning of polymerase activity on G-quadruplex DNA.Human DNA polymerase ε is able to efficiently extend from multiple consecutive ribonucleotides.Trace amounts of 8-oxo-dGTP in mitochondrial dNTP pools reduce DNA polymerase gamma replication fidelity.DNA polymerase epsilon: a polymerase of unusual size (and complexity).Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Zachary Pursell
@ast
Zachary Pursell
@en
Zachary Pursell
@es
Zachary Pursell
@nl
Zachary Pursell
@sl
type
label
Zachary Pursell
@ast
Zachary Pursell
@en
Zachary Pursell
@es
Zachary Pursell
@nl
Zachary Pursell
@sl
prefLabel
Zachary Pursell
@ast
Zachary Pursell
@en
Zachary Pursell
@es
Zachary Pursell
@nl
Zachary Pursell
@sl
P106
P1153
8218176700
P21
P31
P496
0000-0001-5871-7192