Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions
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Development, Maintenance, and Reversal of Multiple Drug Resistance: At the Crossroads of TFPI1, ABC Transporters, and HIF1Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4GWhat Is the Impact of mRNA 5' TL Heterogeneity on Translational Start Site Selection and the Mammalian Cellular Phenotype?New frontiers in translational control of the cancer genomeRLIP76 regulates HIF-1 activity, VEGF expression and secretion in tumor cells, and secretome transactivation of endothelial cells.4EGI-1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance, proliferation and metastasisMNKs act as a regulatory switch for eIF4E1 and eIF4E3 driven mRNA translation in DLBCL.Equol, an isoflavone metabolite, regulates cancer cell viability and protein synthesis initiation via c-Myc and eIF4G.Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.Distinct recruitment of human eIF4E isoforms to processing bodies and stress granulesSystemic Reprogramming of Translation Efficiencies on Oxygen StimulusEukaryotic translation initiation factor 4E as a novel therapeutic target in hematological malignancies and beyond.Association of breast cancer risk and the mTOR pathway in women of African ancestry in 'The Root' Consortium.The Potent Inhibitory Effect of a Naproxen-Appended Cobalt(III)-Cyclam Complex on Cancer Stem Cells.Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation.Translational Dysregulation in Cancer: Molecular Insights and Potential Clinical Applications in Biomarker Development.Expression of eukaryotic initiation factor 4E and 4E binding protein 1 in colorectal carcinogenesis.Role of hypoxia in Diffuse Large B-cell Lymphoma: Metabolic repression and selective translation of HK2 facilitates development of DLBCL.Metformin blocks MYC protein synthesis in colorectal cancer via mTOR-4EBP-eIF4E and MNK1-eIF4G-eIF4E signaling
P2860
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P2860
Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions
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2013 nî lūn-bûn
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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name
Hypoxia-inducible factor-1α (H ...... cells under hypoxia conditions
@en
type
label
Hypoxia-inducible factor-1α (H ...... cells under hypoxia conditions
@en
prefLabel
Hypoxia-inducible factor-1α (H ...... cells under hypoxia conditions
@en
P2093
P2860
P356
P1476
Hypoxia-inducible factor-1α (H ...... cells under hypoxia conditions
@en
P2093
Evangelos Papadopoulos
Gerhard Wagner
Patrick R Hagner
Tingfang Yi
P2860
P304
18732-18742
P356
10.1074/JBC.M113.471466
P407
P577
2013-05-10T00:00:00Z