Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo - Wikidata - awgldk - TriplyDB

Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo

Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo

http://www.wikidata.org/entity/Q36970665

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CD28 co-stimulation down regulates Th17 development Human T regulatory cell therapy: take a billion or so and call me in the morning Inflammatory cytokines in systemic lupus erythematosus The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer Heat shock protein bystander antigens for peptide immunotherapy in autoimmune disease Correlations between psoriasis and inflammatory bowel diseases Indirect recruitment of a CD40 signaling pathway in dendritic cells by B7-DC cross-linking antibody modulates T cell functions.Cancer testis antigen vaccination affords long-term protection in a murine model of ovarian cancer.Roles for inflammation and regulatory T cells in colon cancer.Unifying roles for regulatory T cells and inflammation in cancer.Treatment combining RU486 and Ad5IL-12 vector attenuates the growth of experimentally formed prostate tumors and induces changes in the sentinel lymph nodes of mice Coevolution of TH1, TH2, and TH17 responses during repeated pulmonary exposure to Aspergillus fumigatus conidia.CD39+ regulatory T cells suppress generation and differentiation of Th17 cells in human malignant pleural effusion via a LAP-dependent mechanism Richness and diversity of mammalian fungal communities shape innate and adaptive immunity in health and disease.Cytokines in autoimmunity: role in induction, regulation, and treatment.Interleukin-17 drives pulmonary eosinophilia following repeated exposure to Aspergillus fumigatus conidia.Metabolic regulation of organelle homeostasis in lupus T cells T lymphocytes and normal tissue responses to radiation.Rheumatoid Fibroblast-like Synoviocytes Downregulate Foxp3 Expression by Regulatory T Cells Via GITRL/GITR Interaction Massive ex vivo expansion of human natural regulatory T cells (T(regs)) with minimal loss of in vivo functional activity.Signaling through C5a receptor and C3a receptor diminishes function of murine natural regulatory T cells IDO activates regulatory T cells and blocks their conversion into Th17-like T cells.Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer.A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy TREM-2 mediated signaling induces antigen uptake and retention in mature myeloid dendritic cells.IL-17-producing human peripheral regulatory T cells retain suppressive function.Indoleamine 2,3-dioxygenase controls conversion of Foxp3+ Tregs to TH17-like cells in tumor-draining lymph nodes.Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells.Blockade of interleukin-6 signaling augments regulatory T-cell reconstitution and attenuates the severity of graft-versus-host disease.Cellular immunotherapy for ovarian cancer.Inhibition of CD4+CD25+ regulatory T cell function and conversion into Th1-like effectors by a Toll-like receptor-activated dendritic cell vaccine.Costimulatory pathways in transplantation: challenges and new developments.How diverse--CD4 effector T cells and their functions.IL-17 gene ablation does not impact Treg-mediated suppression of graft-versus-host disease after bone marrow transplantation.Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells.Plasticity of T-cell phenotype and function: the T helper type 17 example.Th17 cytokines and arthritis Suppressive functions of activated B cells in autoimmune diseases reveal the dual roles of Toll-like receptors in immunity.Treating arthritis by immunomodulation: is there a role for regulatory T cells?The impact of Th17 cells on transplant rejection and the induction of tolerance.

P2860

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P2860

Reprogrammed FoxP3+ T regulatory cells become IL-17+ antigen-specific autoimmune effectors in vitro and in vivo

http://www.wikidata.org/entity/Q36970665

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

Reprogrammed FoxP3+ T regulato ...... effectors in vitro and in vivo

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type

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Reprogrammed FoxP3+ T regulato ...... effectors in vitro and in vivo

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Reprogrammed FoxP3+ T regulato ...... effectors in vitro and in vivo

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JIMMUNOL.181.5.3137

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Journal of Immunology

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Reprogrammed FoxP3+ T regulato ...... effectors in vitro and in vivo

@en

P2093

Erin L Schenk

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Larry R Pease

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Michael P Bell

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Pilar Nava-Parada

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Ronald J Marler

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Rosalyn Cabrera

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Sara J Felts

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Suresh Radhakrishnan

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Virginia P Van Keulen

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P2860

A novel transcription factor, T-bet, directs Th1 lineage commitment

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Control of regulatory T cell development by the transcription factor Foxp3

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

Transforming growth factor-beta induces development of the T(H)17 lineage

Helper T cell differentiation is controlled by the cell cycle

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

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3137-3147

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10.4049/JIMMUNOL.181.5.3137

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5

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181

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2008-09-01T00:00:00Z

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18713984

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2582200

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