The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism
about
The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropesBiological function and clinical relevance of chromogranin A and derived peptides.Beta 3-adrenoreceptor regulation of nitric oxide in the cardiovascular system.Catestatin: a multifunctional peptide from chromogranin AChromogranin a and the autonomic system: decomposition of heart rate variability and rescue by its catestatin fragment.Catestatin increases the expression of anti-apoptotic and pro-angiogenetic factors in the post-ischemic hypertrophied heart of SHR.Obligatory role for endothelial heparan sulphate proteoglycans and caveolae internalization in catestatin-dependent eNOS activationChromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364-384))Human catestatin peptides differentially regulate infarct size in the ischemic-reperfused rat heartCatestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart.Direct vasoactive effects of the chromogranin A (CHGA) peptide catestatin in humans in vivo.A novel catestatin-induced antiadrenergic mechanism triggered by the endothelial PI3K-eNOS pathway in the myocardiumCatestatin exerts direct protective effects on rat cardiomyocytes undergoing ischemia/reperfusion by stimulating PI3K-Akt-GSK3β pathway and preserving mitochondrial membrane potentialCorrelation of plasma catestatin level and the prognosis of patients with acute myocardial infarctionHow full is our antihypertensives pipeline?Cardiac and hepatic role of r-AtHSP70: basal effects and protection against ischemic and sepsis conditions.Catestatin (chromogranin A(352-372)) and novel effects on mobilization of fat from adipose tissue through regulation of adrenergic and leptin signaling.Chromogranin A and derived peptides in health and diseaseCatestatin attenuates endoplasmic reticulum induced cell apoptosis by activation type 2 muscarinic acetylcholine receptor in cardiac ischemia/reperfusion.Novel peptide isomer strategy for stable inhibition of catecholamine release: application to hypertensionFunctional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: allele-specific effects on metabolic traits.The extended granin family: structure, function, and biomedical implicationsSerpinins: role in granule biogenesis, inhibition of cell death and cardiac function.Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse.Tumour biomarkers in heart failure: is there a role for CA-125?The important role of catestatin in cardiac remodeling.The surging role of Chromogranin A in cardiovascular homeostasis.Chromogranin A: a paradoxical player in angiogenesis and vascular biology.Recent insights on circulating catecholamines in hypertension.The role of neuropeptides in adverse myocardial remodeling and heart failure.Chromogranin A Regulation of Obesity and Peripheral Insulin Sensitivity.Catestatin reduces myocardial ischaemia/reperfusion injury: involvement of PI3K/Akt, PKCs, mitochondrial KATP channels and ROS signalling.Catestatin Gly364Ser Variant Alters Systemic Blood Pressure and the Risk for Hypertension in Human Populations via Endothelial Nitric Oxide Pathway.Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo.Phosphodiesterase type-2 and NO-dependent S-nitrosylation mediate the cardioinhibition of the antihypertensive catestatin.Catestatin, a chromogranin A-derived peptide, is sympathoinhibitory and attenuates sympathetic barosensitivity and the chemoreflex in rat CVLM.Plasma levels and potential roles of catestatin in patients with coronary heart disease.Akt/eNOS signaling and PLN S-sulfhydration are involved in H₂S-dependent cardiac effects in frog and rat.Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice.Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion.
P2860
Q28579371-A2591FDA-841B-4980-BD34-ED065494248CQ33574106-5DBB5F2E-E40F-4479-9411-A04E48C8FC15Q33838174-E8DE818F-526B-4990-A8DF-6D142047332DQ33838302-B1FA9990-39A1-4CD2-82A4-6D78B1CCAB55Q33874523-116493C6-6FFA-4AF9-9138-D057E2F8C6B9Q34010818-7E07435E-D725-4F24-81F4-38009AD92F8BQ34022482-4591A3FE-FCB8-4F99-9D16-C6733CC3347AQ34376655-5B582150-B0BE-45F2-99CF-5B436406DECFQ34388245-3C22D9FD-E9E5-44D1-9F40-FE6A2E127FB1Q34435168-15536D87-5F9F-4097-9E33-FF1BE624D323Q35027775-43133B87-A9E8-4B68-AEDB-FDA49D4FA621Q35167066-BCF19818-6A27-4F22-960A-BD118B17AF42Q35182058-41881D4B-18EA-44D1-B879-48454C84EAF3Q35303917-FCE7FDFC-3560-47AA-9C40-A309AB1AA47BQ35770676-84316447-658B-42D5-B5B7-E1A19C10480FQ35879483-64154E12-F561-427F-9031-D3036788403AQ36080486-9D857806-2BC5-4D7F-A38D-82B269399852Q36110075-BB74F92F-4273-4662-8989-808B171DC936Q36280742-EA64049A-EDED-4C18-AAE4-CE5C8D873488Q36470847-B1BF2CF7-DEBD-4B6E-9C1B-205329F900D1Q36481887-B40EF055-5D88-4FD5-9B88-960F17B5D453Q36666413-77290414-5EE9-41B7-A7BF-80286ECB6844Q36781898-36D3A40F-0EA6-4D28-B5FD-BC9F517A16ECQ37418242-AA505517-7E21-4DA6-B154-57DFD21381EFQ37869633-8B5CD1BA-1A72-4EED-8F84-BB123C91EC67Q38241244-DDCD7609-D1BA-49F2-B14E-BE1381AA5AF4Q38245248-6C0C21A3-30D1-41D5-A592-D498CAD99298Q38258283-298968C1-876C-44B2-9C5D-42E54443C02FQ38258965-FB44E0A6-CE31-4BE1-A20E-7D394F24B0B5Q39093111-6EA75C70-5151-4F12-B894-179F5BC36339Q39147191-DE4E8C72-BCB2-44F8-A8E2-709A23B6A3D8Q39210583-5DD0BA2D-0B2F-460B-8C5D-ACF36D178FDFQ40690975-60213D63-8D41-417C-9D3D-28521E1892B4Q41138497-6571BFAD-CB61-4A54-88BA-76D30D930A56Q42496988-917742CE-3DBA-45F9-9195-5ADE6A793C12Q42498258-F552AE89-B1DB-4301-9520-CF7E65C5973BQ43442071-D6B67F32-28FB-486B-BA77-7EC2C7E81AA7Q44931953-C7F7DBC3-7FE6-4D80-B5D9-73C901BB600CQ45968038-E9D9EC7C-F6A3-44CD-BA08-39E98A357F29Q46178248-0DD89919-8553-4760-87E6-C4DEA71045D0
P2860
The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The antihypertensive chromogra ...... iac inotropism and lusitropism
@en
type
label
The antihypertensive chromogra ...... iac inotropism and lusitropism
@en
prefLabel
The antihypertensive chromogra ...... iac inotropism and lusitropism
@en
P2093
P2860
P356
P1433
P1476
The antihypertensive chromogra ...... iac inotropism and lusitropism
@en
P2093
Anna Maria Quintieri
Bhawanjit K Brar
Bruno Tota
Pauline T Limchaiyawat
Sushil K Mahata
Tommaso Angelone
P2860
P304
P356
10.1210/EN.2008-0318
P407
P577
2008-06-05T00:00:00Z