The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism - Wikidata - awgldk - TriplyDB

The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism

The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism

http://www.wikidata.org/entity/Q36972684

about

The novel chromogranin A-derived serpinin and pyroglutaminated serpinin peptides are positive cardiac β-adrenergic-like inotropes Biological function and clinical relevance of chromogranin A and derived peptides.Beta 3-adrenoreceptor regulation of nitric oxide in the cardiovascular system.Catestatin: a multifunctional peptide from chromogranin A Chromogranin a and the autonomic system: decomposition of heart rate variability and rescue by its catestatin fragment.Catestatin increases the expression of anti-apoptotic and pro-angiogenetic factors in the post-ischemic hypertrophied heart of SHR.Obligatory role for endothelial heparan sulphate proteoglycans and caveolae internalization in catestatin-dependent eNOS activation Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364-384))Human catestatin peptides differentially regulate infarct size in the ischemic-reperfused rat heart Catestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart.Direct vasoactive effects of the chromogranin A (CHGA) peptide catestatin in humans in vivo.A novel catestatin-induced antiadrenergic mechanism triggered by the endothelial PI3K-eNOS pathway in the myocardium Catestatin exerts direct protective effects on rat cardiomyocytes undergoing ischemia/reperfusion by stimulating PI3K-Akt-GSK3β pathway and preserving mitochondrial membrane potential Correlation of plasma catestatin level and the prognosis of patients with acute myocardial infarction How full is our antihypertensives pipeline?Cardiac and hepatic role of r-AtHSP70: basal effects and protection against ischemic and sepsis conditions.Catestatin (chromogranin A(352-372)) and novel effects on mobilization of fat from adipose tissue through regulation of adrenergic and leptin signaling.Chromogranin A and derived peptides in health and disease Catestatin attenuates endoplasmic reticulum induced cell apoptosis by activation type 2 muscarinic acetylcholine receptor in cardiac ischemia/reperfusion.Novel peptide isomer strategy for stable inhibition of catecholamine release: application to hypertension Functional genetic variants of the catecholamine-release-inhibitory peptide catestatin in an Indian population: allele-specific effects on metabolic traits.The extended granin family: structure, function, and biomedical implications Serpinins: role in granule biogenesis, inhibition of cell death and cardiac function.Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse.Tumour biomarkers in heart failure: is there a role for CA-125?The important role of catestatin in cardiac remodeling.The surging role of Chromogranin A in cardiovascular homeostasis.Chromogranin A: a paradoxical player in angiogenesis and vascular biology.Recent insights on circulating catecholamines in hypertension.The role of neuropeptides in adverse myocardial remodeling and heart failure.Chromogranin A Regulation of Obesity and Peripheral Insulin Sensitivity.Catestatin reduces myocardial ischaemia/reperfusion injury: involvement of PI3K/Akt, PKCs, mitochondrial KATP channels and ROS signalling.Catestatin Gly364Ser Variant Alters Systemic Blood Pressure and the Risk for Hypertension in Human Populations via Endothelial Nitric Oxide Pathway.Impact of Chromogranin A deficiency on catecholamine storage, catecholamine granule morphology and chromaffin cell energy metabolism in vivo.Phosphodiesterase type-2 and NO-dependent S-nitrosylation mediate the cardioinhibition of the antihypertensive catestatin.Catestatin, a chromogranin A-derived peptide, is sympathoinhibitory and attenuates sympathetic barosensitivity and the chemoreflex in rat CVLM.Plasma levels and potential roles of catestatin in patients with coronary heart disease.Akt/eNOS signaling and PLN S-sulfhydration are involved in H₂S-dependent cardiac effects in frog and rat.Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice.Chromogranin A regulates vesicle storage and mitochondrial dynamics to influence insulin secretion.

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P2860

The antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropism

http://www.wikidata.org/entity/Q36972684

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

The antihypertensive chromogra ...... iac inotropism and lusitropism

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type

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The antihypertensive chromogra ...... iac inotropism and lusitropism

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The antihypertensive chromogra ...... iac inotropism and lusitropism

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The antihypertensive chromogra ...... iac inotropism and lusitropism

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P2093

Anna Maria Quintieri

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Bhawanjit K Brar

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Bruno Tota

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Pauline T Limchaiyawat

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Sushil K Mahata

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Tommaso Angelone

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P2860

The catecholamine release-inhibitory "catestatin" fragment of chromogranin a: naturally occurring human variants with different potencies for multiple chromaffin cell nicotinic cholinergic responses

The chromogranin-secretogranin family

Measurements of chromogranin A, chromogranin B (secretogranin I), chromogranin C (secretogranin II) and pancreastatin in plasma and urine from patients with carcinoid tumours and endocrine pancreatic tumours

G protein-mediated inhibitory effect of a nitric oxide donor on the L-type Ca2+ current in rat ventricular myocytes

Modulation of the Ca(2+)-induced Ca(2+) release cascade by beta-adrenergic stimulation in rat ventricular myocytes

Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog

Both rare and common polymorphisms contribute functional variation at CHGA, a regulator of catecholamine physiology.

Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).

A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.

Signalling pathways in cardiac myocyte hypertrophy.

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4780-4793

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scholarly article

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10.1210/EN.2008-0318

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10

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149

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Maria Carmela Cerra

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2008-06-05T00:00:00Z

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18535098

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2582908

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