A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.
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GRK2: multiple roles beyond G protein-coupled receptor desensitizationG Protein-Coupled Receptor Kinases: Crucial Regulators of Blood PressureGRK2 in the heart: a GPCR kinase and beyondG protein-coupled receptor kinase 2: a link between myocardial contractile function and cardiac metabolismG protein-coupled receptor kinase 2, with β-arrestin 2, impairs insulin-induced Akt/endothelial nitric oxide synthase signaling in ob/ob mouse aortaThe expanding GRK interactome: Implications in cardiovascular disease and potential for therapeutic development.G-protein-coupled receptor kinase interactor-1 (GIT1) is a new endothelial nitric-oxide synthase (eNOS) interactor with functional effects on vascular homeostasis.Endothelin antagonism in portal hypertensive mice: implications for endothelin receptor-specific signaling in liver disease.The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.Modulation of pulmonary endothelial endothelin B receptor expression and signaling: implications for experimental hepatopulmonary syndrome.G-protein-coupled-receptor kinases mediate TNFα-induced NFκB signalling via direct interaction with and phosphorylation of IκBα.Mechanisms of regulation and function of G-protein-coupled receptor kinasesVascular signaling through G protein-coupled receptors: new conceptsRegulation of Fc∈RI signaling in mast cells by G protein-coupled receptor kinase 2 and its RH domain.Endothelial nitric-oxide synthase (eNOS) is activated through G-protein-coupled receptor kinase-interacting protein 1 (GIT1) tyrosine phosphorylation and Src proteinLevel of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro- and anti-apoptotic mechanisms.Regulation of GPCR signaling in hypertension.Glytan decreases portal pressure via mesentery vasoconstriction in portal hypertensive rats.Integrin-linked kinase regulates endothelial cell nitric oxide synthase expression in hepatic sinusoidal endothelial cells.Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic PathwayProtein S-nitrosylation in health and disease: a current perspective.G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.G protein coupled receptor kinases as therapeutic targets in cardiovascular disease.G protein-coupled receptor kinases: more than just kinases and not only for GPCRsA Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 UbiquitylationA KSHV microRNA Directly Targets G Protein-Coupled Receptor Kinase 2 to Promote the Migration and Invasion of Endothelial Cells by Inducing CXCR2 and Activating AKT SignalingA KSHV microRNA enhances viral latency and induces angiogenesis by targeting GRK2 to activate the CXCR2/AKT pathway.Myocardial β(2) -adrenoceptor gene delivery promotes coordinated cardiac adaptive remodelling and angiogenesis in heart failure.Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice.S-nitrosylation: integrator of cardiovascular performance and oxygen delivery.Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive ratsCatestatin (chromogranin A344-364) is a novel cardiosuppressive agent: inhibition of isoproterenol and endothelin signaling in the frog heart.Hypertension-associated C825T polymorphism impairs the function of Gβ3 to target GRK2 ubiquitinationThe antihypertensive chromogranin a peptide catestatin acts as a novel endocrine/paracrine modulator of cardiac inotropism and lusitropismThe G-protein-coupled receptor kinase 5 inhibits NFkappaB transcriptional activity by inducing nuclear accumulation of IkappaB alphaCicletanine stimulates eNOS phosphorylation and NO production via Akt and MAP kinase/Erk signaling in sinusoidal endothelial cells.S-nitrosylation of beta-arrestin regulates beta-adrenergic receptor trafficking.Radiofrequency Renal Denervation Protects the Ischemic Heart via Inhibition of GRK2 and Increased Nitric Oxide SignalingDevelopmental and tumoral vascularization is regulated by G protein-coupled receptor kinase 2Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation
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A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension.
description
2005 nî lūn-bûn
@nan
2005 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@ast
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@en
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@nl
type
label
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@ast
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@en
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@nl
prefLabel
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@ast
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@en
A crucial role for GRK2 in reg ...... nction in portal hypertension.
@nl
P2093
P2860
P356
P1433
P1476
A crucial role for GRK2 in reg ...... unction in portal hypertension
@en
P2093
Don C Rockey
Shoukang Zhu
Songling Liu
P2860
P2888
P304
P356
10.1038/NM1289
P407
P577
2005-09-04T00:00:00Z