Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice. - Wikidata - awgldk - TriplyDB

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

http://www.wikidata.org/entity/Q36973521

about

Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids A role for ELOVL4 in the mouse meibomian gland and sebocyte cell biology.Mutant ELOVL4 that causes autosomal dominant stargardt-3 macular dystrophy is misrouted to rod outer segment disks Remodeling adipose tissue through in silico modulation of fat storage for the prevention of type 2 diabetes.Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration Role of long-chain and very-long-chain polyunsaturated fatty acids in macular degenerations and dystrophies Genetics and molecular pathology of Stargardt-like macular degeneration.Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity.Mouse Models of Stargardt 3 Dominant Macular Degeneration Very long chain polyunsaturated fatty acids and rod cell structure and function.Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival.

P2860

Q28592642-12B548B4-4BCB-4C4A-A0ED-26D4126E0863 Q33558508-EBA0FE08-1957-49B3-B06B-6FA4867E8C3A Q33761007-BE094ACC-1A60-44B2-A33C-B5B038EC307A Q33791444-7B4FCD48-64B2-42B7-AAE3-3F6B655F5629 Q33902007-A1181A61-E65A-4CCC-857A-503E574D553B Q34157723-1A4AFE0C-752A-42F2-B69B-99F4F011053C Q34334822-EEEE211A-62DE-4944-9D63-48215302D8FE Q34691651-FCA4279E-22F2-456A-81F9-F8873EBFF286 Q35633398-E1ED71DB-0F05-4734-B99B-522C700E7B77 Q37665462-4F095CB9-9F9B-4679-BE78-B0A5F9F4336E Q38596864-90242BCE-78B1-478D-94DF-E890E6120784 Q42716287-9216F7E1-F907-4654-B2F2-B176FDFDF5D8 Q42957838-B0D94A8C-C6B2-4886-9726-2C6AAE9A2DDF

P2860

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

http://www.wikidata.org/entity/Q36973521

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

2007年论文

@zh

2007年论文

@zh-cn

name

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

@en

type

label

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

@en

prefLabel

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

@en

P1433

Q36973521-20842CBF-C2CA-42BA-9A97-3EA324151531

P1476

Q36973521-630E8C87-6B3B-4F0D-9BCA-7461CA06DEF5

P2093

Q36973521-2BE2438C-FEB6-47CB-9239-CB7D40449434

Q36973521-3F890309-37BB-4478-93ED-2D4C0431D513

Q36973521-4C600A1A-429C-49A4-B069-8A2658EBE315

Q36973521-63E555AB-A7AF-452E-8AA2-045BDB6B0366

Q36973521-7754FE5B-0536-41F2-9022-288FF558A79C

Q36973521-7A22CB69-A8DD-4E87-A16F-1C008C3F204E

Q36973521-97E1E9ED-F094-44AE-AF29-65FA8A5D27AB

Q36973521-AB83F17D-90C5-44D4-894D-DA06A8458553

Q36973521-CD0ABE8E-D397-4AE1-A15C-52E38C77870E

Q36973521-E5D81892-03A7-4281-9674-A33FA4C2B222

P2860

Q36973521-2AF1896D-A4DB-4F60-A58B-812E3323EF29

Q36973521-45A542A7-5AD8-4D31-9A1A-623173E8B2C1

Q36973521-5AA4FB1C-0450-4007-8D7D-8002A24674B6

Q36973521-67CDAC84-DAE9-4998-9B92-AF4AA86C689A

Q36973521-7A63DFA1-185D-4EF0-9B5C-65044EC1A162

Q36973521-84B0ED60-49DF-4D7A-A52F-EA3568617E65

Q36973521-9CD7863A-4A0C-440E-95A2-8FF823F1F24F

Q36973521-B14F55E2-FCA3-4195-93C9-712E9CBC2B5D

Q36973521-BFFF3BCD-29C7-480E-A18D-D8B739E55017

Q36973521-D89F9BBD-BFB7-48E4-9B55-763AABA1D699

P304

Q36973521-A0ADFE3A-7610-4FCA-B741-D83F9567BC93

P31

Q36973521-91A07110-EF40-4FE8-A0F8-F5B458A74679

P356

Q36973521-3714E637-572D-4E18-9F17-A71AB1D0DD87

P433

Q36973521-505DCBB9-75D2-4D9B-9320-8D3E0B0E37E1

P478

Q36973521-A8159B8C-137A-428C-8E93-D6B457CBDF63

P577

Q36973521-2ED0E559-CA09-40E0-916D-6AA116F5BCFF

P5875

Q36973521-C505DC4C-885D-40CF-A3CF-F3D3E4943DAE

P698

Q36973521-C567A847-2388-49C1-A86D-76333348EA9A

P921

Q36973521-815381AE-8405-4250-A144-8E8E6B561720

P932

Q36973521-741ECB9E-6D47-4CAB-9A2E-E6FFD7FF7F00

P356

J.VISRES.2006.10.023

P1433

Vision Research

P1476

Elovl4 haploinsufficiency does not induce early onset retinal degeneration in mice.

@en

P2093

Changguan Wang

http://www.w3.org/2001/XMLSchema#string

Chuxia Deng

http://www.w3.org/2001/XMLSchema#string

D Joshua Cameron

http://www.w3.org/2001/XMLSchema#string

Erik Pearson

http://www.w3.org/2001/XMLSchema#string

Goutam Karan

http://www.w3.org/2001/XMLSchema#string

Haoyu Chen

http://www.w3.org/2001/XMLSchema#string

Kang Zhang

http://www.w3.org/2001/XMLSchema#string

Kimberly Howes

http://www.w3.org/2001/XMLSchema#string

Wenmei Li

http://www.w3.org/2001/XMLSchema#string

Yali Chen

http://www.w3.org/2001/XMLSchema#string

P2860

A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy

Dominant negative mechanism underlies autosomal dominant Stargardt-like macular dystrophy linked to mutations in ELOVL4

Cloning of a human cDNA encoding a novel enzyme involved in the elongation of long-chain polyunsaturated fatty acids

Resonance Raman evidence for an Fe-O-Fe center in stearoyl-ACP desaturase. Primary sequence identity with other diiron-oxo proteins

Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase

Lipofuscin accumulation, abnormal electrophysiology, and photoreceptor degeneration in mutant ELOVL4 transgenic mice: a model for macular degeneration.

The fatty acid chain elongation system of mammalian endoplasmic reticulum.

The metabolism of omega-3 polyunsaturated fatty acids in the eye: the possible role of docosahexaenoic acid and docosanoids in retinal physiology and ocular pathology.

A novel mutation in the ELOVL4 gene causes autosomal dominant Stargardt-like macular dystrophy.

Role of a new mammalian gene family in the biosynthesis of very long chain fatty acids and sphingolipids.

P304

714-722

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.VISRES.2006.10.023

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

47

http://www.w3.org/2001/XMLSchema#string

P577

2007-01-24T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6548820

http://www.w3.org/2001/XMLSchema#string

P698

17254625

http://www.w3.org/2001/XMLSchema#string

P921

haploinsufficiency

P932

2583245

http://www.w3.org/2001/XMLSchema#string