Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
about
Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and ArthritisMicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.The chemokine receptor CXCR2 ligand KC (CXCL1) mediates neutrophil recruitment and is critical for development of experimental Lyme arthritis and carditis.Different patterns of expression and of IL-10 modulation of inflammatory mediators from macrophages of Lyme disease-resistant and -susceptible mice.Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins.Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation5-Lipoxygenase-deficient mice infected with Borrelia burgdorferi develop persistent arthritis.Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infectionNovel microbial virulence factor triggers murine lyme arthritis.T Cells Exacerbate Lyme Borreliosis in TLR2-Deficient Mice.Localized production of IL-10 suppresses early inflammatory cell infiltration and subsequent development of IFN-γ-mediated Lyme arthritisEndothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue.
P2860
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P2860
Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
@en
type
label
Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
@en
prefLabel
Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
@en
P2093
P2860
P356
P1476
Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease
@en
P2093
Annie Y-C Lai
Jennifer M Hughes
Steven T Callen
William J Mitchell
P2860
P304
P356
10.1128/IAI.00808-08
P407
P577
2008-09-29T00:00:00Z