Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease - Wikidata - awgldk - TriplyDB

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

http://www.wikidata.org/entity/Q36974456

about

Antagonistic Interplay between MicroRNA-155 and IL-10 during Lyme Carditis and Arthritis MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi.The chemokine receptor CXCR2 ligand KC (CXCL1) mediates neutrophil recruitment and is critical for development of experimental Lyme arthritis and carditis.Different patterns of expression and of IL-10 modulation of inflammatory mediators from macrophages of Lyme disease-resistant and -susceptible mice.Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins.Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation 5-Lipoxygenase-deficient mice infected with Borrelia burgdorferi develop persistent arthritis.Dietary fish oil substitution alters the eicosanoid profile in ankle joints of mice during Lyme infection Novel microbial virulence factor triggers murine lyme arthritis.T Cells Exacerbate Lyme Borreliosis in TLR2-Deficient Mice.Localized production of IL-10 suppresses early inflammatory cell infiltration and subsequent development of IFN-γ-mediated Lyme arthritis Endothelial cells and fibroblasts amplify the arthritogenic type I IFN response in murine Lyme disease and are major sources of chemokines in Borrelia burgdorferi-infected joint tissue.

P2860

Q27300844-565109E9-CC6B-42E3-85F8-437776957250 Q33812777-DE6E90F3-24B8-4407-87EE-7DAD68B08E22 Q34290822-69D49C3B-66A1-4DE2-B635-45FA3DC826C1 Q34424975-2A27D9DC-9644-4E40-8332-E96F82DDBEBD Q35347078-4783B2FE-DF79-4A91-8B84-A08B71DFEB18 Q35598063-FB0F114C-AB12-44EA-B943-0EE455962EB3 Q35940546-F31E6865-83D2-4A38-92C9-30841DE9FCEE Q36096352-CD73ADF2-FC91-4819-B3B4-1F3B444B693F Q36607282-1DFC306A-645A-4102-AE8A-4E54871138B4 Q37389932-F943A784-414F-4A63-96F9-5929B43366BC Q40557771-2C325333-A40E-4AF3-B38A-696BBDDC247B Q42108192-3C8753B8-BA19-4259-8DDC-3069ABABE8A7

P2860

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

http://www.wikidata.org/entity/Q36974456

description

2008 nî lūn-bûn

@nan

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

2008年论文

@zh

2008年论文

@zh-cn

name

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

@en

type

label

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

@en

prefLabel

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

@en

P1433

Q36974456-B77E7712-3072-47E8-9132-F52107229C5D

P1476

Q36974456-39590C57-4116-461E-8BCD-77BCF03499AE

P2093

Q36974456-38D042B0-EFF6-4D49-BFA6-78EB47712032

Q36974456-5711BE7C-F4D5-442B-A1AA-2183541DAE8B

Q36974456-99B08296-B63C-4CC0-99A1-670B6FDB4DFD

Q36974456-ADC8CF65-FA0B-4B25-A6D9-85E81E3531E6

P2860

Q36974456-068BBCE2-0154-41B8-965F-B0B0D7DCFA06

Q36974456-06F18465-A2C5-43F9-9650-B419FF4E65DD

Q36974456-0A227694-9D9F-40C9-8FA6-50693AB8FC56

Q36974456-14337AAA-0030-46AA-B418-79471AA742B3

Q36974456-276E4581-E011-4492-8EB1-08BFFB3003F8

Q36974456-2CAA68AA-4270-4E2D-8EF5-360C0C734AAD

Q36974456-344C67D2-2A48-44FF-949A-74FC3558263D

Q36974456-470F84B5-D807-4C89-B84F-AA0AEC6E1EDF

Q36974456-4AC184CA-FE91-46FF-893E-1BF1B7BB5D70

Q36974456-55DC64AD-C5AA-494C-932E-C78E4599AB1D

P304

Q36974456-F73BC10D-39EB-402C-8EF9-BF33F8290260

P31

Q36974456-A721E233-73B8-42C2-9140-401A869A0C50

P356

Q36974456-52B0E483-E369-4E71-87E2-13EE1CBAAF99

P407

Q36974456-D6050D4C-E755-4DC7-A5F1-81D3F3F70AC5

P433

Q36974456-7CBB389F-8F50-4981-8ED6-5FA528DE2420

P478

Q36974456-F405B372-5E81-4C1C-B0F5-0AED1D7F0785

P50

Q36974456-989D19E2-C553-4E55-B798-493723A9B0AF

Q36974456-DAE4DE6C-28F0-4031-8805-9EFE1C0FF153

P577

Q36974456-8CFC87F3-10D1-43CA-998D-1EA25D1E29DF

P698

Q36974456-F5A0E5A6-CD03-4ADD-82B1-864A318FE0AC

P921

Q36974456-1D1EE734-6807-4BA1-A76B-69DA2872BBB5

Q36974456-46573530-B749-4D69-9054-5C2C78A6A020

P932

Q36974456-87DE8443-ED5B-4C4E-8C50-E22491044E5C

P356

P1433

Infection and Immunity

P1476

Adenoviral delivery of interleukin-10 fails to attenuate experimental Lyme disease

@en

P2093

Annie Y-C Lai

http://www.w3.org/2001/XMLSchema#string

Jennifer M Hughes

http://www.w3.org/2001/XMLSchema#string

Steven T Callen

http://www.w3.org/2001/XMLSchema#string

William J Mitchell

http://www.w3.org/2001/XMLSchema#string

P2860

Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI

Interleukin-10 determines viral clearance or persistence in vivo

Macrophages and their products in rheumatoid arthritis

T cell cytokine pattern in the joints of patients with Lyme arthritis and its regulation by cytokines and anticytokines

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

IL-10 inhibits cytokine production by activated macrophages

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice.

Clearance of Borrelia burgdorferi may not be required for resistance to experimental lyme arthritis.

Borrelia burgdorferi stimulates the production of interleukin-10 in peripheral blood mononuclear cells from uninfected humans and rhesus monkeys.

P304

5500-5507

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1128/IAI.00808-08

http://www.w3.org/2001/XMLSchema#string

P407

P433

12

http://www.w3.org/2001/XMLSchema#string

P478

76

http://www.w3.org/2001/XMLSchema#string

P50

Charles R Brown

Victoria A Blaho

P577

2008-09-29T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

18824530

http://www.w3.org/2001/XMLSchema#string

P921

P932

2583579

http://www.w3.org/2001/XMLSchema#string