Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death. - Wikidata - awgldk - TriplyDB

Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death.

Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death.

http://www.wikidata.org/entity/Q36979129

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Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Integration of Mitochondrial Targeting for Molecular Cancer Therapeutics Metabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implication Targeting mitochondria metabolism for cancer therapy Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis.Combined inhibition of glycolysis and AMPK induces synergistic breast cancer cell killing.ROS homeostasis and metabolism: a dangerous liason in cancer cells Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments.Selective Vulnerability of Cancer Cells by Inhibition of Ca(2+) Transfer from Endoplasmic Reticulum to Mitochondria Bioenergetic properties of human sarcoma cells help define sensitivity to metabolic inhibitors.Effect of mitochondrially targeted carboxy proxyl nitroxide on Akt-mediated survival in Daudi cells: Significance of a dual mode of action Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism Steroid receptor coactivator-3 regulates glucose metabolism in bladder cancer cells through coactivation of hypoxia inducible factor 1α.High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.Low dose of 2-deoxy-D-glucose kills acute lymphoblastic leukemia cells and reverses glucocorticoid resistance via N-linked glycosylation inhibition under normoxia.Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation.Syrosingopine sensitizes cancer cells to killing by metformin Repositioning of Verrucosidin, a purported inhibitor of chaperone protein GRP78, as an inhibitor of mitochondrial electron transport chain complex I.Mitochondria-targeted vitamin E analogs inhibit breast cancer cell energy metabolism and promote cell death.Dual-targeting of aberrant glucose metabolism in glioblastoma Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss.Inhibition of KIT-glycosylation by 2-deoxyglucose abrogates KIT-signaling and combination with ABT-263 synergistically induces apoptosis in gastrointestinal stromal tumor.A novel class of mitochondria-targeted soft electrophiles modifies mitochondrial proteins and inhibits mitochondrial metabolism in breast cancer cells through redox mechanisms.Manganese (III) meso-tetrakis N-ethylpyridinium-2-yl porphyrin acts as a pro-oxidant to inhibit electron transport chain proteins, modulate bioenergetics, and enhance the response to chemotherapy in lymphoma cells.Mortalin (GRP75/HSPA9) upregulation promotes survival and proliferation of medullary thyroid carcinoma cells.Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling Preventing Allograft Rejection by Targeting Immune Metabolism.Therapeutic Targeting of the Mitochondria Initiates Excessive Superoxide Production and Mitochondrial Depolarization Causing Decreased mtDNA Integrity Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea.Oxidants, antioxidants and the current incurability of metastatic cancers.Breast tumor and stromal cell responses to TGF-β and hypoxia in matrix deposition.Mitochondria-targeted nitroxide, Mito-CP, suppresses medullary thyroid carcinoma cell survival in vitro and in vivo.Does scavenging of mitochondrial superoxide attenuate cancer prosurvival signaling pathways?Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells Iron chelators target both proliferating and quiescent cancer cells.Stress-related mitochondrial components and mitochondrial genome as targets of anticancer therapy.Targeting mitochondrial function for the treatment of breast cancer.Mitochondria-targeted drug delivery system for cancer treatment.

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P2860

Mitochondria-targeted drugs synergize with 2-deoxyglucose to trigger breast cancer cell death.

http://www.wikidata.org/entity/Q36979129

description

2012 nî lūn-bûn

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2012年论文

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2012年论文

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2012年论文

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name

Mitochondria-targeted drugs sy ...... gger breast cancer cell death.

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Mitochondria-targeted drugs sy ...... gger breast cancer cell death.

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Mitochondria-targeted drugs sy ...... gger breast cancer cell death.

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Mitochondria-targeted drugs sy ...... gger breast cancer cell death.

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Balaraman Kalyanaraman

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Brian P Dranka

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Donna McAllister

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Gang Cheng

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Jacek Zielonka

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Joy Joseph

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P2860

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

HIF-1 and tumor progression: pathophysiology and therapeutics

Glycolysis inhibition for anticancer treatment

Metabolic modulation of glioblastoma with dichloroacetate

Why do cancers have high aerobic glycolysis?

Cancer cell metabolism: Warburg and beyond

Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells

Preclinical evaluation of novel triphenylphosphonium salts with broad-spectrum activity

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity

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