A data-based assessment of alternative strategies for identification of potential human cancer hazards.
about
Prediction of the Carcinogenic Potential of Human Pharmaceuticals Using Repeated Dose Toxicity Data and Their Pharmacological Properties.Data mining in the U.S. National Toxicology Program (NTP) database reveals a potential bias regarding liver tumors in rodents irrespective of the test agent.Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activatorAlternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.Improving prediction of carcinogenicity to reduce, refine, and replace the use of experimental animals.Relationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework.Editor's Highlight: Negative Predictors of Carcinogenicity for Environmental Chemicals.Human and environmental health challenges for the next decade (2010–2020).Opportunities for an alternative integrating testing strategy for carcinogen hazard assessment?Human and primate-specific microRNAs in cancer: Evolution, and significance in comparison with more distantly-related research models: The great potential of evolutionary young microRNA in cancer research.Hepatic microRNA profiles offer predictive and mechanistic insights after exposure to genotoxic and epigenetic hepatocarcinogens.Primate-specific Long Non-coding RNAs and MicroRNAs.Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors. II: Additional Mechanistic Studies.Involvement of Mouse Constitutive Androstane Receptor in Acifluorfen-Induced Liver Injury and Subsequent Tumor Development.Comparative time course profiles of phthalate stereoisomers in mice.Sex differences in blood genotoxic and cytotoxic effects as a consequence of vanadium inhalation: micronucleus assay evaluation.Chronic progressive nephropathy in male F344 rats in 90-day toxicity studies: its occurrence and association with renal tubule tumors in subsequent 2-year bioassays.An integrative test strategy for cancer hazard identification.Revisiting alternative approaches to the assessment of carcinogenic risk.
P2860
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P2860
A data-based assessment of alternative strategies for identification of potential human cancer hazards.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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name
A data-based assessment of alt ...... otential human cancer hazards.
@ast
A data-based assessment of alt ...... otential human cancer hazards.
@en
type
label
A data-based assessment of alt ...... otential human cancer hazards.
@ast
A data-based assessment of alt ...... otential human cancer hazards.
@en
prefLabel
A data-based assessment of alt ...... otential human cancer hazards.
@ast
A data-based assessment of alt ...... otential human cancer hazards.
@en
P2093
P2860
P356
P1476
A data-based assessment of alt ...... otential human cancer hazards.
@en
P2093
Douglas C Wolf
Frederick G Hess
Gordon C Hard
James S Macdonald
Nancy G Doerrer
Patrick J Haley
Samuel M Cohen
Sheila M Galloway
Stéphane Thibault
P2860
P304
P356
10.1177/0192623309343779
P407
P577
2009-08-21T00:00:00Z