The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation. - Wikidata - awgldk - TriplyDB

The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.

The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.

http://www.wikidata.org/entity/Q36980688

about

Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61 Group 1 mGluR-dependent synaptic long-term depression: mechanisms and implications for circuitry and disease Protein phosphatases and Alzheimer's disease Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function Amyloid-β-Induced Dysregulation of AMPA Receptor Trafficking Emerging Link between Alzheimer's Disease and Homeostatic Synaptic Plasticity Cellular biochemistry methods for investigating protein tyrosine phosphatases The pathophysiology of fragile X (and what it teaches us about synapses)Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes Inhibition of the tyrosine phosphatase STEP61 restores BDNF expression and reverses motor and cognitive deficits in phencyclidine-treated mice.Striatal-enriched protein tyrosine phosphatase in Alzheimer's disease.Metabotropic glutamate receptor dependent long-term depression in the cortex Striatal-enriched protein tyrosine phosphatase expression and activity in Huntington's disease: a STEP in the resistance to excitotoxicity STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Calpain and STriatal-Enriched protein tyrosine phosphatase (STEP) activation contribute to extrasynaptic NMDA receptor localization in a Huntington's disease mouse model The tyrosine phosphatase STEP: implications in schizophrenia and the molecular mechanism underlying antipsychotic medications Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase.Inhibitor of the tyrosine phosphatase STEP reverses cognitive deficits in a mouse model of Alzheimer's disease Checking the STEP-Associated Trafficking and Internalization of Glutamate Receptors for Reduced Cognitive Deficits: A Machine Learning Approach-Based Cheminformatics Study and Its Application for Drug Repurposing Extrasynaptic NMDA receptors couple preferentially to excitotoxicity via calpain-mediated cleavage of STEP A substrate trapping mutant form of striatal-enriched protein tyrosine phosphatase prevents amphetamine-induced stereotypies and long-term potentiation in the striatum Cellular distribution of AMPA receptor subunits and mGlu5 following acute and repeated administration of morphine or methamphetamine Phosphorylation of FMRP and alterations of FMRP complex underlie enhanced mLTD in adult rats triggered by early life seizures.From FMRP function to potential therapies for fragile X syndrome.Metabotropic glutamate receptors: from the workbench to the bedside.The Role of Proteases in Hippocampal Synaptic Plasticity: Putting Together Small Pieces of a Complex Puzzle.Computational identification of potential multitarget treatments for ameliorating the adverse effects of amyloid-β on synaptic plasticity Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism Reduced levels of the tyrosine phosphatase STEP block β amyloid-mediated GluA1/GluA2 receptor internalization Therapeutic implications for striatal-enriched protein tyrosine phosphatase (STEP) in neuropsychiatric disorders.Protein tyrosine phosphatases as potential therapeutic targets.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Disruption of striatal-enriched protein tyrosine phosphatase (STEP) function in neuropsychiatric disorders Homeostatic scaling requires group I mGluR activation mediated by Homer1a.Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway STEP regulation of seizure thresholds in the hippocampus.Oxidative stress-induced oligomerization inhibits the activity of the non-receptor tyrosine phosphatase STEP61.Protein tyrosine phosphatase receptor type R is required for Purkinje cell responsiveness in cerebellar long-term depression

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P2860

The tyrosine phosphatase STEP mediates AMPA receptor endocytosis after metabotropic glutamate receptor stimulation.

http://www.wikidata.org/entity/Q36980688

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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2008年论文

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2008年论文

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name

The tyrosine phosphatase STEP ...... lutamate receptor stimulation.

@en

type

label

The tyrosine phosphatase STEP ...... lutamate receptor stimulation.

@en

prefLabel

The tyrosine phosphatase STEP ...... lutamate receptor stimulation.

@en

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JNEUROSCI.2666-08.2008

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Journal of Neuroscience

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The tyrosine phosphatase STEP ...... glutamate receptor stimulation

@en

P2093

Clare M Gladding

http://www.w3.org/2001/XMLSchema#string

Deepa V Venkitaramani

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Graham L Collingridge

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Paul J Lombroso

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Pradeep Kurup

http://www.w3.org/2001/XMLSchema#string

Yang Zhang

http://www.w3.org/2001/XMLSchema#string

Yongfang Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Differential interaction of the tyrosine phosphatases PTP-SL, STEP and HePTP with the mitogen-activated protein kinases ERK1/2 and p38alpha is determined by a kinase specificity sequence and influenced by reducing agents

Regulation of NMDA receptor trafficking by amyloid-beta

NMDA-mediated activation of the tyrosine phosphatase STEP regulates the duration of ERK signaling

Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation

Cellular and molecular characterization of a brain-enriched protein tyrosine phosphatase

Rap1-induced p38 mitogen-activated protein kinase activation facilitates AMPA receptor trafficking via the GDI.Rab5 complex. Potential role in (S)-3,5-dihydroxyphenylglycene-induced long term depression

Receptor trafficking and synaptic plasticity

The striatal-enriched protein tyrosine phosphatase gates long-term potentiation and fear memory in the lateral amygdala

Synaptic plasticity: one STEP at a time.

Tyrosine phosphatase STEP is a tonic brake on induction of long-term potentiation.

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10561-10566

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10.1523/JNEUROSCI.2666-08.2008

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42

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2008-10-01T00:00:00Z

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18923032

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2586105

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