Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells.
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Genetically manipulated mouse models of lung disease: potential and pitfallsIncreased eicosanoid levels in the Sugen/chronic hypoxia model of severe pulmonary hypertensionThe key role of PGC-1α in mitochondrial biogenesis and the proliferation of pulmonary artery vascular smooth muscle cells at an early stage of hypoxic exposureThe Critical Role of Pulmonary Arterial Compliance in Pulmonary Hypertension.Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia.Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.Pulmonary oxidative stress is increased in cyclooxygenase-2 knockdown mice with mild pulmonary hypertension induced by monocrotalineTargeted deletions of cyclooxygenase-2 and atherogenesis in mice.Sex hormones and vascular protection in pulmonary arterial hypertension.Regulation of rat intrapulmonary arterial tone by arachidonic acid and prostaglandin E2 during hypoxia.Effects of chrysin (5,7-dihydroxyflavone) on vascular remodeling in hypoxia-induced pulmonary hypertension in ratsRole of prostacyclin in pulmonary hypertension.EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling.Cyclooxygenase-2 deficiency leads to intestinal barrier dysfunction and increased mortality during polymicrobial sepsis.Influence of obesity and metabolic dysfunction on the endothelial control in the coronary circulation.Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling.Silencing of sodium-hydrogen exchanger 1 attenuates the proliferation, hypertrophy, and migration of pulmonary artery smooth muscle cells via E2F1Distal vessel stiffening is an early and pivotal mechanobiological regulator of vascular remodeling and pulmonary hypertensionCyclooxygenase-2 inhibition and hypoxia-induced pulmonary hypertension: effects on pulmonary vascular remodeling and contractilityExpression profile of mitochondrial voltage-dependent anion channel-1 (VDAC1) influenced genes is associated with pulmonary hypertension.The principal pathways involved in the in vivo modulation of hypoxic pulmonary vasoconstriction, pulmonary arterial remodelling and pulmonary hypertension.Drug-induced pulmonary arterial hypertension: a review.Inflammatory Markers for Arterial Stiffness in Cardiovascular Diseases.MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension: results of a network bioinformatics approach.Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries.Hypoxia-induced hyperreactivity of pulmonary arteries: role of cyclooxygenase-2, isoprostanes, and thromboxane receptors.Genetic deletion of aquaporin-1 results in microcardia and low blood pressure in mouse with intact nitric oxide-dependent relaxation, but enhanced prostanoids-dependent relaxation.Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2.NOD2 deficiency exacerbates hypoxia-induced pulmonary hypertension and enhances pulmonary vascular smooth muscle cell proliferation.
P2860
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P2860
Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Absence of cyclooxygenase-2 ex ...... vascular smooth muscle cells.
@en
type
label
Absence of cyclooxygenase-2 ex ...... vascular smooth muscle cells.
@en
prefLabel
Absence of cyclooxygenase-2 ex ...... vascular smooth muscle cells.
@en
P2093
P2860
P1433
P1476
Absence of cyclooxygenase-2 ex ...... vascular smooth muscle cells.
@en
P2093
Alvaro A Macias
Dario F Riascos
Laura E Fredenburgh
Mark A Perrella
Olin D Liang
S Alex Mitsialis
Scott L Schissel
Stella Kourembanas
Su Wol Chung
Thomas R Polte
P2860
P304
P356
10.1161/CIRCULATIONAHA.107.716241
P407
P577
2008-04-07T00:00:00Z