Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension
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Hypoxia upregulates PGI-synthase and increases PGI₂ release in human vascular cells exposed to inflammatory stimuliGenomic approaches to research in pulmonary hypertensionAn efficient method to successively introduce transgenes into a given genomic locus in the mouseInhaled therapy for the management of perioperative pulmonary hypertensionIloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungsGenetically manipulated mouse models of lung disease: potential and pitfallsA brief overview of mouse models of pulmonary arterial hypertension: problems and prospects.Attenuation of monocrotaline-induced pulmonary hypertension by luminal adeno-associated virus serotype 9 gene transfer of prostacyclin synthaseInternalization and sequestration of the human prostacyclin receptor.Pulmonary oxidative stress is increased in cyclooxygenase-2 knockdown mice with mild pulmonary hypertension induced by monocrotalineThe lung HETEs (and EETs) up.Sex hormones and vascular protection in pulmonary arterial hypertension.Pharmacologic treatments for pulmonary hypertension: exploring pharmacogenomicsNew treatments for pulmonary arterial hypertension.Epithelial EGF receptor signaling mediates airway hyperreactivity and remodeling in a mouse model of chronic asthma.Acceleration of atherogenesis by COX-1-dependent prostanoid formation in low density lipoprotein receptor knockout mice.Chemoprevention of murine lung cancer by gefitinib in combination with prostacyclin synthase overexpression.Pulmonary hypertension in the young.Paracrine effects of bone marrow-derived endothelial progenitor cells: cyclooxygenase-2/prostacyclin pathway in pulmonary arterial hypertension.S100A4/Mts1 produces murine pulmonary artery changes resembling plexogenic arteriopathy and is increased in human plexogenic arteriopathyRole of prostacyclin in pulmonary hypertension.EP3 receptor deficiency attenuates pulmonary hypertension through suppression of Rho/TGF-β1 signaling.Pulmonary hypertension in chronic obstructive pulmonary disease: current theories of pathogenesis and their implications for treatment.Prostacyclin prevents pulmonary endothelial cell apoptosis induced by cigarette smoke.The role of peroxisome proliferator-activated receptors in pulmonary vascular disease.Improved pulmonary vascular reactivity and decreased hypertrophic remodeling during nonhypercapnic acidosis in experimental pulmonary hypertension.Molecular mechanisms regulating the vascular prostacyclin pathways and their adaptation during pregnancy and in the newborn.Cyclooxygenase-1 overexpression decreases Basal airway responsiveness but not allergic inflammation.Vascular dysfunction in a murine model of severe hemolysis.Differences between basal lung levels of select eicosanoids in rat and mousePathophysiology of pulmonary arterial hypertension.Future perspectives for the treatment of pulmonary arterial hypertension.Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells.Role of chemokine C-C motif ligand-1 in acute and chronic pulmonary inflammationsPGI synthase overexpression protects against bleomycin-induced mortality and is associated with increased Nqo 1 expressionProstacyclin prevents murine lung cancer independent of the membrane receptor by activation of peroxisomal proliferator--activated receptor gamma.Inhaled iloprost for the control of pulmonary hypertension.Prostacyclin-mediated activation of peroxisome proliferator-activated receptor delta in colorectal cancer.Selective inhibition of prostacyclin synthase activity by rofecoxib.Pulmonary perfusion imaging in the rodent lung using dynamic contrast-enhanced MRI.
P2860
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P2860
Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension
description
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im Juni 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/06/01)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/06/01)
@nl
наукова стаття, опублікована в червні 1999
@uk
مقالة علمية (نشرت في يونيو 1999)
@ar
name
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@ast
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@en
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@nl
type
label
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@ast
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@en
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@nl
prefLabel
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@ast
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@en
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@nl
P2093
P2860
P921
P3181
P356
P1476
Pulmonary prostacyclin synthas ...... hypoxic pulmonary hypertension
@en
P2093
D. C. Shepherd
J. Y. Westcott
K. A. Fagan
L. A. Alger
M. D. Moore
M. W. Geraci
N. F. Voelkel
R. M. Tuder
P2860
P304
P3181
P356
10.1172/JCI5911
P407
P577
1999-06-01T00:00:00Z