Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes.
about
Pachymic acid inhibits growth and induces apoptosis of pancreatic cancer in vitro and in vivo by targeting ER stressActivation of nerve growth factor-induced B alpha by methylene-substituted diindolylmethanes in bladder cancer cells induces apoptosis and inhibits tumor growth1,1-Bis(3'-indolyl)-1-(p-bromophenyl)methane and related compounds repress survivin and decrease gamma-radiation-induced survivin in colon and pancreatic cancer cellsInactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth.Chemoprevention of skin cancer with 1,1-Bis (3'-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1)Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumorsThe orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells.Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells.HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer.(E)-2,4-bis(p-hydroxyphenyl)-2-butenal has an antiproliferative effect on NSCLC cells induced by p38 MAPK-mediated suppression of NF-κB and up-regulation of TNFRSF10B (DR5).Mechanisms and therapeutic implications of cell death induction by indole compounds.1,1-Bis (3'-indolyl)-1-(p-substitutedphenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model.TR3 modulates platinum resistance in ovarian cancer.Targeting NR4A1 (TR3) in cancer cells and tumorsNovel diindolylmethane derivatives based NLC formulations to improve the oral bioavailability and anticancer effects in triple negative breast cancer.Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity.A Metabolic Inhibitory Cocktail for Grave Cancers: Metformin, Pioglitazone and Lithium Combination in Treatment of Pancreatic Cancer and Glioblastoma Multiforme.3,3'-diindolylmethane induces activating transcription factor 3 (ATF3) via ATF4 in human colorectal cancer cells.β-Phenethyl isothiocyanate induces death receptor 5 to induce apoptosis in human oral cancer cells via p38.Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs).Oxidized analogs of Di(1H-indol-3-yl)methyl-4-substituted benzenes are NR4A1-dependent UPR inducers with potent and safe anti-cancer activity.
P2860
Q21090555-980670DB-5E21-4ED5-AD35-7191BF8BC9AAQ33714685-729BA8CE-7FC3-4B55-B7A6-D5F350001158Q33748743-3AFC5429-B817-4DF8-931C-2C3D0360FFF1Q34334258-7EB3A356-5011-4032-9D23-CD936823B0EBQ34946349-744AD1CF-5C77-4C48-BEB8-F250E45B951EQ35020448-948CF311-5BDF-4C04-BEFA-AD2FD03288E0Q35530854-48E2A063-48CC-4412-8DAA-BB681F783797Q36126761-02AA8E78-9B5B-4097-9552-67518EE5104AQ36357062-912B214B-4421-43CE-988E-480CE806DDD5Q36681789-696C0E39-E5A5-438B-B12C-4BBE01601808Q37137367-8A64C262-AFA9-46DC-B438-F95143B5B868Q37338514-F34D1CA9-1292-4B7D-B413-A76B5D0DA7C6Q37620325-B531AB26-1743-49CF-B56D-0D1B5B25A641Q37825901-BDD551F2-1DA2-464B-8AD0-E5F76B8B14EFQ38748639-4D307910-80E4-4050-B79C-2661DAD4222CQ38863616-DE6CEB8B-1C0F-4938-8A51-40D455EAE9FAQ38885892-B5294133-90B0-435A-B5B1-27D29C98E032Q39310806-CBED5048-0965-4595-BDE4-5E7B34398B75Q39400925-08D6BFC1-7AA4-492E-BA50-6E107ED63F63Q41561405-FD62721F-05E8-4130-99FC-30C7626D1517Q55397738-266B45B3-78E1-4FEB-A8CE-14C650981CED
P2860
Structure-dependent activation of endoplasmic reticulum stress-mediated apoptosis in pancreatic cancer by 1,1-bis(3'-indoly)-1-(p-substituted phenyl)methanes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Structure-dependent activation ...... p-substituted phenyl)methanes.
@en
type
label
Structure-dependent activation ...... p-substituted phenyl)methanes.
@en
prefLabel
Structure-dependent activation ...... p-substituted phenyl)methanes.
@en
P2093
P2860
P1476
Structure-dependent activation ...... p-substituted phenyl)methanes.
@en
P2093
Maen Abdelrahim
Stephen Safe
Sung Dae Cho
P2860
P304
P356
10.1158/1535-7163.MCT-08-0439
P577
2008-10-01T00:00:00Z