The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation
about
DRiPs solidify: progress in understanding endogenous MHC class I antigen processingPrimary sterile necrotic cells fail to cross-prime CD8(+) T cellsIdentification of chaperones as essential components of the tumor rejection moieties of cancersCompartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action.Direct presentation regulates the magnitude of the CD8+ T cell response to cell-associated antigen through prolonged T cell proliferation.Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase.Fishing for the hidden peptidome in health and disease (drug abuse)Peptidomic analysis of human cell lines.Prolonged antigen presentation following an acute virus infection requires direct and then cross-presentation.Variable HIV peptide stability in human cytosol is critical to epitope presentation and immune escape.Heat shock protein 90 (HSP90) contributes to cytosolic translocation of extracellular antigen for cross-presentation by dendritic cellsVariable processing and cross-presentation of HIV by dendritic cells and macrophages shapes CTL immunodominance and immune escape.Heat shock proteins and cancer vaccines: developments in the past decade and chaperoning in the decade to comeChemokines control naive CD8+ T cell selection of optimal lymph node antigen presenting cells.Tumor-derived autophagosome vaccine: induction of cross-protective immune responses against short-lived proteins through a p62-dependent mechanism.Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptidesMHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. viral mRNA.Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy.Proteasomes, TAP, and endoplasmic reticulum-associated aminopeptidase associated with antigen processing control CD4+ Th cell responses by regulating indirect presentation of MHC class II-restricted cytoplasmic antigensMixed proteasomes function to increase viral peptide diversity and broaden antiviral CD8+ T cell responsesPeptidases released by necrotic cells control CD8+ T cell cross-priming.Vaccinia virus CD8+ T-cell dominance hierarchies cannot be altered by prior immunization with individual peptides.Efficient cross-priming of antiviral CD8+ T cells by antigen donor cells is GRP94 independentThe amino acid sequences flanking an antigenic determinant can strongly affect MHC class I cross-presentation without altering direct presentation.Designing CD8+ T cell vaccines: it's not rocket science (yet).Translating DRiPs: progress in understanding viral and cellular sources of MHC class I peptide ligands.Melanoma vaccines: developments over the past 10 years.The role of heat shock proteins in antigen cross presentation.Immunogenicity of necrotic cell death.Lymph node - an organ for T-cell activation and pathogen defense.Quantitating MHC class I ligand production and presentation using TCR-like antibodies.The outcome of cross-priming during virus infection is not directly linked to the ability of the antigen to be cross-presented.Mature proteins derived from Epstein-Barr virus fail to feed into the MHC class I antigenic pool.Increasing antigen presentation on HSV-1-infected cells increases lesion size but does not alter neural infection or latency.
P2860
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P2860
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The exception that reinforces ...... ptides that escape degradation
@en
type
label
The exception that reinforces ...... ptides that escape degradation
@en
prefLabel
The exception that reinforces ...... ptides that escape degradation
@en
P2093
P2860
P1433
P1476
The exception that reinforces ...... ptides that escape degradation
@en
P2093
Avital Lev
Christopher V Nicchitta
Damien Zanker
Didier Picard
Elizabeth Waffarn
Jack R Bennink
James Gibbs
Jason C Maynard
Kazuyo Takeda
Len Neckers
P2860
P304
P356
10.1016/J.IMMUNI.2008.04.015
P407
P577
2008-06-01T00:00:00Z