Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
about
The molecular basis of hereditary 1,25-dihydroxyvitamin D3 resistant rickets in seven related familiesPoint mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistanceGeneralized glucocorticoid resistance: clinical aspects, molecular mechanisms, and implications of a rare genetic disorderLinking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric DisordersChrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changesRaised urinary glucocorticoid and adrenal androgen precursors in the urine of young hypertensive patients: possible evidence for partial glucocorticoid resistanceA novel point mutation of the human glucocorticoid receptor gene causes primary generalized glucocorticoid resistance through impaired interaction with the LXXLL motif of the p160 coactivators: dissociation of the transactivating and transreppressivThe human glucocorticoid receptor: molecular basis of biologic functionA mutation of the glucocorticoid receptor in primary cortisol resistance.Primary generalized familial and sporadic glucocorticoid resistance (Chrousos syndrome) and hypersensitivitySteroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapyRecent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor.Primary cortisol resistance associated with a thermolabile glucocorticoid receptor in a patient with fatigue as the only symptom.The pharmacogenetics of asthma: a candidate gene approach.Impact of glucocorticoid receptor density on ligand-independent dimerization, cooperative ligand-binding and basal priming of transactivation: a cell culture model.The glucocorticoid receptor gene and its association to metabolic syndrome.Resistance to 1,25-dihydroxyvitamin D. Association with heterogeneous defects in cultured skin fibroblasts.Are BDNF and glucocorticoid activities calibrated?A novel point mutation in the DNA-binding domain (DBD) of the human glucocorticoid receptor causes primary generalized glucocorticoid resistance by disrupting the hydrophobic structure of its DBD.Impaired stimulation of 25-hydroxyvitamin D-24-hydroxylase in fibroblasts from a patient with vitamin D-dependent rickets, type II. A form of receptor-positive resistance to 1,25-dihydroxyvitamin D3.Effects of Chronic ACTH Excess on Human Adrenal Cortex.Chrousos syndrome: from molecular pathogenesis to therapeutic management.Recruitment of cAMP-response element-binding protein and histone deacetylase has opposite effects on glucocorticoid receptor gene transcriptionGlucocorticoid resistance in asthma.Dexamethasone regulation of glycosaminoglycan synthesis in cultured human skin fibroblasts. Similar effects of glucocorticoid and thyroid hormonesInduction of corticosteroid resistance in vitro.Lack of mutations in the gene coding for the hGR (NR3C1) in a pediatric patient with ACTH-secreting pituitary adenoma, absence of stigmata of Cushing's syndrome and unusual histologic features.The regulation of the 17-deoxy steroids in man.A novel mutation of the hGR gene causing Chrousos syndrome.Primary generalized glucocorticoid resistance and hypersensitivity: the end-organ involvement in the stress response.Functional characterization of the hGRαT556I causing Chrousos syndrome.Thyroid and glucocorticoid hormone regulation of specific protein abundance in cultured human skin fibroblasts.An unexpected, mild phenotype of glucocorticoid resistance associated with glucocorticoid receptor gene mutation case report and review of the literature.
P2860
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P2860
Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
description
1982 nî lūn-bûn
@nan
1982年の論文
@ja
1982年論文
@yue
1982年論文
@zh-hant
1982年論文
@zh-hk
1982年論文
@zh-mo
1982年論文
@zh-tw
1982年论文
@wuu
1982年论文
@zh
1982年论文
@zh-cn
name
Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
@en
type
label
Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
@en
prefLabel
Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
@en
P2093
P2860
P356
P1476
Primary cortisol resistance in man. A glucocorticoid receptor-mediated disease
@en
P2093
Chrousos GP
DeVroede M
Lipsett MB
Loriaux DL
Vingerhoeds A
P2860
P304
P356
10.1172/JCI110565
P407
P577
1982-06-01T00:00:00Z